Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …

The interaction of coagulation factors with the perivascular environment affects the
development of disease in ways that extend beyond their traditional roles in the acute …

A microglial cell is both a glial cell of the central nervous system and a mononuclear
phagocyte, which belongs to the haematopoietic system and is involved in inflammatory and …

The blood–brain barrier (BBB) is formed primarily to protect the brain microenvironment from
the influx of plasma components, which may disturb neuronal functions. The BBB is a …

The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

Microglia are resident cells of the brain involved in regulatory processes critical for
development, maintenance of the neural environment, injury and repair. They belong to the …

Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …

Traumatic damage to the central nervous system (CNS) destroys the blood–brain barrier
(BBB) and provokes the invasion of hematogenous cells into the neural tissue. Invading …

Fibrosis is the aberrant deposition of extracellular matrix (ECM) components during tissue
healing leading to loss of its architecture and function. Fibrotic diseases are often associated …

Microglia are a heterogenous group of monocyte-derived cells serving multiple roles within
the brain, many of which are associated with immune and macrophage like properties …