[HTML][HTML] Application of pseudovirus system in the development of vaccine, antiviral-drugs, and neutralizing antibodies

Q Xiang, L Li, J Wu, M Tian, Y Fu - Microbiological Research, 2022 - Elsevier
Pseudoviruses are viral particles coated with a heterologous envelope protein, which
mediates the entry of pseudoviruses as efficiently as that of the live viruses possessing high …

SARS-CoV-2 B. 1.617. 2 Delta variant replication and immune evasion

P Mlcochova, SA Kemp, MS Dhar, G Papa, B Meng… - Nature, 2021 - nature.com
Abstract The B. 1.617. 2 (Delta) variant of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread …

Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles

AM Syed, TY Taha, T Tabata, IP Chen, A Ciling… - Science, 2021 - science.org
Efforts to determine why new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …

[HTML][HTML] Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7

B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira… - Cell reports, 2021 - cell.com
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70
in multiple independent lineages, often occurring after acquisition of receptor binding motif …

[PDF][PDF] The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry

TP Peacock, JC Brown, J Zhou, N Thakur… - …, 2022 - pdfs.semanticscholar.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …

Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants

AK Reuschl, LG Thorne, MVX Whelan… - Nature …, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …

A prenylated dsRNA sensor protects against severe COVID-19

A Wickenhagen, E Sugrue, S Lytras, S Kuchi… - Science, 2021 - science.org
INTRODUCTION Interferons (IFNs) are cytokines that are rapidly deployed in response to
invading pathogens. By initiating a signaling cascade that stimulates the expression of …

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

A Fendler, STC Shepherd, L Au, KA Wilkinson, M Wu… - Nature cancer, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune
monitoring (CAPTURE)(NCT03226886) is a prospective cohort study of COVID-19 immunity …

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

BJ Willett, J Grove, OA MacLean, C Wilkie, N Logan… - MedRxiv, 2022 - medrxiv.org
Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …

First cases of SARS-CoV-2 BA. 2.86 in Denmark, 2023

M Rasmussen, FT Møller, V Gunalan, S Baig… - …, 2023 - eurosurveillance.org
We describe 10 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant BA. 2.86 detected in Denmark, including molecular characteristics and results from …