Endothelial tight junctions (TJs) regulate the transport of water, ions, and molecules through
the paracellular pathway, serving as an important barrier in blood vessels and maintaining …

In recent years there has been a resurgence of interest in brain barriers and various roles
their intrinsic mechanisms may play in neurological disorders. Such studies require suitable …

Traumatic brain injury (TBI) can lead to disability or devastating consequences with few
established treatments. Although ferroptosis has been shown to be involved in TBI, the …

Macrolides are a diverse class of hydrophobic compounds characterized by a macrocyclic
lactone ring and distinguished by variable side chains/groups. Some of the most well …

Sodium butyrate (SB) has been widely used to treat cerebral diseases. The aim of the
present study is to examine the neuroprotective effects of SB on early TBI in mice and to …

Mild blast-induced traumatic brain injury (TBI) is associated with blood-brain barrier (BBB)
disruption. However, the mechanisms whereby blast disrupts BBB integrity are not well …

Injury severity in blast induced Traumatic Brain Injury (bTBI) increases with blast
overpressure (BOP) and impulse in dose-dependent manner. Pure primary blast waves …

Recent evidence linking repeated low-level blast overpressure exposure in operational and
training environments with neurocognitive decline, neuroinflammation, and …

Blast-related traumatic brain injury (TBI) has received much recent attention because of its
frequency in the conflicts in Iraq and Afghanistan. This renewed interest has led to a rapid …

Much concern exists over the role of blast-induced traumatic brain injury (TBI) in the chronic
cognitive and mental health problems that develop in veterans and active duty military …