The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

The need for new classes of antiretroviral drugs has become apparent because of
increasing concern about the long-term toxic effects of existing drugs, the need to combat …

Multiple genome-wide studies have identified associations between outcome of human
immunodeficiency virus (HIV) infection and polymorphisms in and around the gene …

Variants near the HLA-DP gene show the strongest genome-wide association with chronic
hepatitis B virus (HBV) infection and HBV recovery/persistence in Asians. To test the effect of …

Abstract (See the editorial commentary by Peters and Marston, on pages 166–8.)
Background. Understanding the impact of hepatitis B virus (HBV) in human …

Chronic hepatitis B virus (HBV) infection remains a leading cause of hepatic inflammation
and damage. The pathogenesis of chronic hepatitis B (CHB) infection is predominantly …

The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …

Since the discovery of CCR5 as a coreceptor for HIV entry, there has been interest in
blockade of the receptor for treatment and prevention of HIV infection. Although several …

The field of pharmacogenetics, the investigation of the influence of one or more sequence
variants on drug response phenotypes, is a special case of pharmacogenomics, a discipline …

An IL28B haplotype strongly determines the outcome of natural and interferon-α treated
hepatitis C virus (HCV) infection. To assess whether the polymorphism marking the …