IS Waddell, C Orfila - Critical reviews in food science and nutrition, 2023 - Taylor & Francis
Obesity is a mostly preventable diet-related disease and currently a major challenge for human populations worldwide. Obesity is a major risk factor for diseases such as type 2 …
T van Deuren, EE Blaak, EE Canfora - Obesity Reviews, 2022 - Wiley Online Library
Evidence is increasing that disturbances in the gut microbiome may play a significant role in the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …
Y Tong, S Xu, L Huang, C Chen - Drug Discovery Today, 2022 - Elsevier
The prevalence of obesity is a major cause of many chronic metabolic disorders, including type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), and cancer. Insulin …
SR Talbot, S Biernot, A Bleich, RM van Dijk… - Laboratory …, 2020 - journals.sagepub.com
In many animal experiments scientists and local authorities define a body-weight reduction of 20% or more as severe suffering and thereby as a potential parameter for humane …
JE Lewis, FJP Ebling, RJ Samms, K Tsintzas - Trends in Endocrinology & …, 2019 - cell.com
Fibroblast growth factor 21 (FGF21) is a protein highly synthesized in the liver that exerts paracrine and endocrine control of many aspects of energy homeostasis in multiple tissues …
B Leppert, S Strunz, B Seiwert, L Schlittenbauer… - Nature …, 2020 - nature.com
Parabens are preservatives widely used in consumer products including cosmetics and food. Whether low-dose paraben exposure may cause adverse health effects has been …
Obesity is a chronic, multifactorial, and morbid disease. In the United States, 69% of adults are overweight or have obesity, and the global prevalence of obesity is increasing. Obesity …
Obesity is primarily a consequence of consuming calories beyond energetic requirements, but underpinning drivers have not been fully defined. 5-Hydroxytryptamine (5-HT) neurons …
L Cifuentes, A Acosta - Clinics and research in hepatology and …, 2022 - Elsevier
Food intake and energy expenditure are key regulators of body weight. To regulate food intake, the brain must integrate physiological signals and hedonic cues. The brain plays an …