Nanoparticles‐induced potential toxicity on human health: applications, toxicity mechanisms, and evaluation models

L Xuan, Z Ju, M Skonieczna, PK Zhou, R Huang - MedComm, 2023 - Wiley Online Library
Nanoparticles (NPs) have become one of the most popular objects of scientific study during
the past decades. However, despite wealth of study reports, still there is a gap, particularly in …

[HTML][HTML] Design of biopolymer-based hemostatic material: Starting from molecular structures and forms

CY Zou, QJ Li, JJ Hu, YT Song, QY Zhang, R Nie… - Materials Today Bio, 2022 - Elsevier
Uncontrolled bleeding remains as a leading cause of death in surgical, traumatic, and
emergency situations. Management of the hemorrhage and development of hemostatic …

Hemostasis without clot formation–how platelets guard the vasculature in inflammation, infection, and malignancy

R Kaiser, R Escaig, L Nicolai - Blood, 2023 - Elsevier
Platelets are key vascular effectors in hemostasis, with activation signals leading to fast
recruitment, aggregation, and clot formation. The canonical process of hemostasis is well …

Catechol-chitosan/carboxymethylated cotton-based Janus hemostatic patch for rapid hemostasis in coagulopathy

Q Xu, E Hu, H Qiu, L Liu, Q Li, B Lu, K Yu, F Lu… - Carbohydrate …, 2023 - Elsevier
Uncontrolled bleeding is the leading cause of death, and the death risk of bleeding from
coagulopathy is even higher. By infusing the relevant coagulation factors, bleeding in …

Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models

S Roullet, N Luc, J Rayes, J Solarz… - Blood, The Journal …, 2023 - ashpublications.org
The lack of innovation in von Willebrand disease (VWD) originates from many factors
including the complexity and heterogeneity of the disease but also from a lack of recognition …

Platelet Membrane‐Derived Nanodiscs for Neutralization of Endogenous Autoantibodies and Exogenous Virulence Factors

L Sun, Y Yu, Y Peng, D Wang, S Wang, I Noh, RH Fang… - Small, 2024 - Wiley Online Library
The multifaceted functions of platelets in various physiological processes have long inspired
the development of therapeutic nanoparticles that mimic specific platelet features for disease …

Highly efficient photoelectrochemical aptasensor based on CdS/CdTe QDs co-sensitized TiO2 nanoparticles designed for thrombin detection

X Xu, Y Lu, D Liu, L Zhang, L Zheng, G Nie - Microchimica Acta, 2024 - Springer
A photoelectrochemical (PEC) sensor for the sensitive detection of thrombin (TB) was
established. Co-sensitized combination of TiO2 nanoparticles combined with modified …

[HTML][HTML] Treatment of inherited platelet disorders: current status and future options

C Bargehr, R Knöfler, W Streif - Hämostaseologie, 2023 - thieme-connect.com
Inherited platelet disorders (IPDs) comprise a heterogeneous group of entities that manifest
with variable bleeding tendencies. For successful treatment, the underlying platelet disorder …

Recent Advances in Topical Hemostatic Materials

Y Liu, Y Zhang, W Yao, P Chen, Y Cao… - ACS Applied Bio …, 2024 - ACS Publications
Untimely or improper treatment of traumatic bleeding may cause secondary injuries and
even death. The traditional hemostatic modes can no longer meet requirements of coping …

Self-Oxidated Hydrophilic Chitosan Fibrous Mats for Fatal Hemorrhage Control

J Shi, K Shi, Q Dong, J Yang, Y Zhou… - … Applied Materials & …, 2024 - ACS Publications
Enriching erythrocytes and platelets in seconds and providing a fast seal in bleeding sites is
vital to fatal hemorrhage control. Herein, hydrophilic chitosan fibrous mats (CECS-D mats) …