Interleukin-10-1082 promoter polymorphism in association with cytokine production and sepsis susceptibility

SA Stanilova, LD Miteva, ZT Karakolev… - Intensive care …, 2006 - Springer
Objective To investigate the-1082 (A/G) polymorphism in the promoter of the IL-10 gene in
terms of IL-10 production from stimulated peripheral blood mononuclear cells (PBMC) and to …

Taq-I polymorphism in 3′ UTR of the IL-12B and association with IL-12p40 production from human PBMC

S Stanilova, L Miteva - Genes & Immunity, 2005 - nature.com
A wide array of studies has demonstrated differences in genotype and allele frequencies of
cytokine gene polymorphisms depending on ethnicity and race. In this study, the frequency …

The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes

ZG Dobreva, LD Miteva… - Immunopharmacology and …, 2009 - Taylor & Francis
Interleukin-10 is the most important anti-inflammatory cytokine that controls the progress of
the immune response. The molecular mechanisms driving the IL10 gene regulation are not …

High interleukin 12 and low interleukin 10 production after in vitro stimulation detected in sepsis survivors

SA Stanilova, ZT Karakolev, GS Dimov… - Intensive Care …, 2005 - Springer
Objective To evaluate viability of isolated peripheral blood mononuclear cells (PBMC) and
production of cytokines in vitro after stimulation as prognostic factors for survival in sepsis …

Circulating immune complexes among diabetic children

G Nicoloff, A Blazhev, C Petrova… - Journal of Immunology …, 2004 - Wiley Online Library
Insulin dependent diabetes mellitus (IDDM) is an autoimmune disease associated with the
presence of different types of autoantibodies. The presence of these antibodies and the …

Comparative study of circulating immune complexes quantity detection by three assays—CIF-ELISA, C1q-ELISA and anti-C3 ELISA

SA Stanilova, ES Slavov - Journal of immunological methods, 2001 - Elsevier
The assessment of the soluble immune complexes (IC) in human sera is traditionally
performed by the C1q binding assay. In the present study, a novel method for the quantity of …

[PDF][PDF] Cytokine production in thromboangiitis obliterans patients: new evidence for an immune-mediated inflammatory disorder

ES Slavov, SA Stanilova, DP Petkov… - Clin Exp …, 2005 - researchgate.net
Abstract Objective To study IL-6, IL-10, IL-12 levels and circulating immune complexes (CIC)
containing IgG, IgM or IgA in sera of 14 TAO patients and 12 healthy blood donors. To …

The combined effect of interleukin (IL)-10 and IL-12 polymorphisms on induced cytokine production

L Miteva, S Stanilova - Human immunology, 2008 - Elsevier
Interleukin (IL)-12 and IL-10 are immunoregulatory cytokines with an antagonistic effect of
the T-helper (Th) 1/Th2 cytokine balance and provide a functional link between innate and …

C3 binding glycoprotein from Cuscuta europea induced different cytokine profiles from human PBMC compared to other plant and bacterial immunomodulators

SA Stanilova, ZG Dobreva, ES Slavov… - International …, 2005 - Elsevier
The immunomodulatory properties of bioactive agents include the ability to induce cytokine
production by the activated target cell. The effect of immunomodulatory C3 binding …

Structural and Immunological Characterization of the Cuscuta pentagona L. Chloroplast

TD Sherman, WT Pettigrew… - Plant and Cell …, 1999 - academic.oup.com
Structural and immunochemical studies were used to determine the photosynthetic potential
of the dodder (Cuscuta pentagona) chloroplast. Ultrastructural studies revealed that …