The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Precise and sensitive analysis of exosomal microRNA (miRNA) is of great importance for
noninvasive early disease diagnosis, but it remains a great challenge to detect exosomal …

INTRODUCTION Since the 1980s, the design and synthesis of molecular machines has
been identified as a grand challenge for molecular engineering. Robots are an important …

Nucleic acids are considered as perfect programmable materials for cascade signal
amplification and not merely as genetic information carriers. Among them, catalytic hairpin …

Synthetic DNA motors have great potential to mimic natural protein motors in cells but the
operation of synthetic DNA motors in living cells remains challenging and has not been …

MicroRNA (miRNA) imaging in disease sites is vital to elucidate their role in cancer
progression. However, limited tumor specificity remains a major barrier for traditional …

Designer DNA nanodevices have attracted extensive interest for detection of specific targets
in living cells. However, it still remains a great challenge to construct DNA sensing devices …

DNA‐based machines have attracted rapidly growing interest owing to their potential in drug
delivery, biocomputing, and diagnostic applications. Herein, we report a type of exonuclease …

Sensitive and accurate analysis of low‐concentration of tumor‐derived exosomes (Exos) in
biofluids is essential for noninvasive cancer diagnosis but is still challenging due to the lack …