[HTML][HTML] Cisplatin-induced ototoxicity: From signaling network to therapeutic targets

X Wang, Y Zhou, D Wang, Y Wang, Z Zhou… - Biomedicine & …, 2023 - Elsevier
Administration of cisplatin, a common chemotherapeutic drug, has an inevitable side effect
of sensorineural hearing loss. The main etiologies are stria vascularis injury, spiral ganglion …

Emerging roles of the membrane potential: action beyond the action potential

L Abdul Kadir, M Stacey, R Barrett-Jolley - Frontiers in physiology, 2018 - frontiersin.org
Whilst the phenomenon of an electrical resting membrane potential (RMP) is a central tenet
of biology, it is nearly always discussed as a phenomenon that facilitates the propagation of …

Bioelectric signaling as a unique regulator of development and regeneration

MP Harris - Development, 2021 - journals.biologists.com
It is well known that electrical signals are deeply associated with living entities. Much of our
understanding of excitable tissues is derived from studies of specialized cells of neurons or …

Age-related changes in the cochlea and vestibule: shared patterns and processes

V Paplou, NMA Schubert, SJ Pyott - Frontiers in neuroscience, 2021 - frontiersin.org
Both age-related hearing loss (ARHL) and age-related loss in vestibular function (ARVL) are
prevalent conditions with deleterious consequences on the health and quality of life. Age …

Hearing function, degeneration, and disease: Spotlight on the stria vascularis

MR Thulasiram, JM Ogier, A Dabdoub - Frontiers in Cell and …, 2022 - frontiersin.org
The stria vascularis (SV) is a highly vascularized tissue lining the lateral wall of the cochlea.
The SV maintains cochlear fluid homeostasis, generating the endocochlear potential that is …

[图书][B] Sensory transduction

GL Fain - 2019 - books.google.com
How are sights and sounds and smells converted into electrical signals in a form that can be
interpreted by the nervous system? Although this process, called sensory transduction …

Update on findings about sudden sensorineural hearing loss and insight into its pathogenesis

S Yamada, J Kita, D Shinmura, Y Nakamura… - Journal of Clinical …, 2022 - mdpi.com
Sudden sensorineural hearing loss (SSNHL) is routinely encountered and is one of the most
common emergent diseases in otolaryngology clinics. However, the etiology of SSNHL …

Semicircular canal biomechanics in health and disease

RD Rabbitt - Journal of Neurophysiology, 2019 - journals.physiology.org
The semicircular canals are responsible for sensing angular head motion in three-
dimensional space and for providing neural inputs to the central nervous system (CNS) …

Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway

B Peixoto Pinheiro, B Vona, H Löwenheim… - … -European Journal of …, 2021 - Springer
Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly and
constitutes the third highest risk factor for dementia. Lifetime noise exposure, genetic …

Pharmacological Approaches to Hearing Loss

CR Cederroth… - Pharmacological …, 2024 - pharmrev.aspetjournals.org
Hearing disorders pose significant challenges to individuals experiencing them and their
overall quality of life, emphasizing the critical need for advanced pharmacological …