Cardiovascular function and treatment in β-thalassemia major: a consensus statement from the American Heart Association

DJ Pennell, JE Udelson, AE Arai, B Bozkurt… - Circulation, 2013 - Am Heart Assoc
This aim of this statement is to report an expert consensus on the diagnosis and treatment of
cardiac dysfunction in β-thalassemia major (TM). This consensus statement does not cover …

L-carnitine supplementation: influence upon physiological function

WJ Kraemer, JS Volek… - Current sports medicine …, 2008 - journals.lww.com
Abstract Carnitine (L-3-hydroxytrimethylamminobutanoate) is a naturally occurring
compound that can be synthesized in mammals from the essential amino acids lysine and …

[HTML][HTML] Role of carnitine in cancer chemotherapy-induced multiple organ toxicity

MM Sayed-Ahmed - Saudi pharmaceutical journal, 2010 - Elsevier
In the last few years, cancer chemotherapy has been successfully employed in the treatment
of different types of human tumours. Unfortunately, the optimal clinical usefulness of this …

[HTML][HTML] L-carnitine supplementation improves hematological pattern in patients affected by HCV treated with Peg interferon-α 2b plus ribavirin

M Malaguarnera, M Vacante, M Giordano… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To evaluate the efficacy of L-carnitine on alleviating anemia, thrombocytopenia and
leukopenia, and minimizing dose reductions in patients with chronic hepatitis C virus (HCV) …

Placebo effect and athletes

TH Trojian, CJ Beedie - Current sports medicine reports, 2008 - journals.lww.com
Anecdotal and experimental evidence suggest that the placebo effect is seen in athletics. To
this end, placebos have been used in clinical practice and athletic performance. Positive …

Carnitine–acylcarnitine translocase deficiency: Two neonatal cases with common splicing mutation and in vitro bezafibrate response

N Vatanavicharn, K Yamada, Y Aoyama, T Fukao… - Brain and …, 2015 - Elsevier
Background Mitochondrial fatty acid oxidation (FAO) disorders are among the causes of
acute encephalopathy-or myopathy-like illness. Carnitine–acylcarnitine translocase (CACT) …

Exercise performance in thalassemia major: correlation with cardiac iron burden

EY Sohn, R Kato, LJ Noetzli, A Gera… - American journal of …, 2013 - Wiley Online Library
Exercise performance is decreased in patients with Thalassemia major (TM), but the relative
impact of anemia and iron overload on exercise capacity is unknown. We assessed the …

Determining and surveying the role of carnitine and folic acid to decrease fatigue in β-thalassemia minor subjects

SMB Tabei, M Mazloom, M Shahriari… - Pediatric hematology …, 2013 - Taylor & Francis
Beta-thalassemia minor (BTM) patients usually experience fatigue, bone pain complaint,
and muscle weakness. Carnitine is an essential protein for transportation of long-chain fatty …

Recent progress in gene therapy and other targeted therapeutic approaches for beta thalassemia

EM Hamed, MH Meabed, UF Aly… - Current Drug …, 2019 - ingentaconnect.com
Beta-thalassemia is a genetic disorder characterized by the impaired synthesis of the
betaglobin chain of adult hemoglobin. The disorder has a complex pathophysiology that …

[HTML][HTML] Impaired acylcarnitine profile in transfusion-dependent beta-thalassemia major patients in Bangladesh

SK Sarker, MT Islam, GS Bhuyan, N Sultana… - Journal of Advanced …, 2018 - Elsevier
Patients with beta-thalassemia major (BTM) suffer from fatigue, poor physical fitness, muscle
weakness, lethargy, and cardiac complications which are related to an energy crisis …