[HTML][HTML] FGF/FGFR signaling: From lung development to respiratory diseases

L Yang, F Zhou, D Zheng, D Wang, X Li, C Zhao… - Cytokine & growth factor …, 2021 - Elsevier
The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling system
regulates a variety of biological processes, including embryogenesis, angiogenesis, wound …

[HTML][HTML] Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis

A Wu, B Feng, J Yu, L Yan, L Che, Y Zhuo, Y Luo, B Yu… - Redox Biology, 2021 - Elsevier
Ferroptosis plays a role in several diseases such as iron overload-induced liver diseases.
Manipulation of ferroptosis has been explored as a potential therapeutic strategy to treat …

[HTML][HTML] Exerkines and redox homeostasis

E Félix-Soriano, KI Stanford - Redox Biology, 2023 - Elsevier
Exercise physiology has gained increasing interest due to its wide effects to promote health.
Recent years have seen a growth in this research field also due to the finding of several …

Physical exercise, health, and disease treatment: The role of macrophages

IOM Callegari, GZ Rocha, AG Oliveira - Frontiers in Physiology, 2023 - frontiersin.org
Subclinical inflammation is linked to comorbidities and risk factors, consolidating the
diagnosis of chronic non-communicable diseases, such as insulin resistance …

Modeling diet-induced NAFLD and NASH in rats: a comprehensive review

L Carreres, ZM Jílková, G Vial, PN Marche, T Decaens… - Biomedicines, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease,
characterized by hepatic steatosis without any alcohol abuse. As the prevalence of NAFLD …

Physical activity protocols in non-alcoholic fatty liver disease management: A systematic review of randomized clinical trials and animal models

E Barron-Cabrera, R Soria-Rodriguez, F Amador-Lara… - Healthcare, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is closely associated with other metabolic disease
and cardiovascular disease. Regular exercise reduces hepatic fat content and could be the …

Utility of human relevant preclinical animal models in navigating NAFLD to MAFLD paradigm

D Chua, ZS Low, GX Cheam, AS Ng… - International Journal of …, 2022 - mdpi.com
Fatty liver disease is an emerging contributor to disease burden worldwide. The past
decades of work established the heterogeneous nature of non-alcoholic fatty liver disease …

Research Progress on Lipophagy-Mediated Exercise Intervention in Non-Alcoholic Fatty Liver Disease

X Li, Y Yang, Y Sun, S Ding - International Journal of Molecular Sciences, 2024 - mdpi.com
Lipophagy is a cellular pathway targeting the lysosomal degradation of lipid droplets,
playing a role in promoting lipid turnover and renewal. Abnormal lipophagy processes can …

[HTML][HTML] Exercise in mice ameliorates high-fat diet-induced nonalcoholic fatty liver disease by lowering HMGCS2

X Qian, T Wang, J Gong, L Wang, X Chen, H Lin… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease worldwide.
Exercise is a therapeutic strategy for preventing NAFLD. However, the underlying molecular …

Investigation of FGF21 mRNA levels and relative mitochondrial DNA copy number levels and their relation in nonalcoholic fatty liver disease: a case-control study

M Houshmand, V Zeinali, A Hosseini, A Seifi… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Although the exact mechanisms of nonalcoholic fatty liver disease (NAFLD) are
not fully understood, numerous pieces of evidence show that the variations in mitochondrial …