Gold nanozymes: from concept to biomedical applications

J Lou-Franco, B Das, C Elliott, C Cao - Nano-Micro Letters, 2021 - Springer
In recent years, gold nanoparticles have demonstrated excellent enzyme-mimicking
activities which resemble those of peroxidase, oxidase, catalase, superoxide dismutase or …

Insights on catalytic mechanism of CeO2 as multiple nanozymes

Y Ma, Z Tian, W Zhai, Y Qu - Nano Research, 2022 - Springer
CeO2 with the reversible Ce3+/Ce4+ redox pair exhibits multiple enzyme-like catalytic
performance, which has been recognized as a promising nanozyme with potentials for …

Nanomaterial-based bioorthogonal nanozymes for biological applications

S Fedeli, J Im, S Gopalakrishnan, JL Elia… - Chemical Society …, 2021 - pubs.rsc.org
Bioorthogonal transformations are chemical reactions that use pathways which biological
processes do not access. Bioorthogonal chemistry provides new approaches for imaging …

Filling in the gaps between nanozymes and enzymes: challenges and opportunities

Y Zhou, B Liu, R Yang, J Liu - Bioconjugate chemistry, 2017 - ACS Publications
Using nanomaterials to mimic the function of protein enzymes is an interesting idea. Many
nanomaterials have a similar size as enzymes and they also possess catalytic activity. Over …

Degradable ZnS-supported bioorthogonal nanozymes with enhanced catalytic activity for intracellular activation of therapeutics

X Zhang, S Lin, R Huang, A Gupta… - Journal of the …, 2022 - ACS Publications
Bioorthogonal catalysis using transition-metal catalysts (TMCs) provides a toolkit for the in
situ generation of imaging and therapeutic agents in biological environments. Integrating …

Advances in organometallic/organic nanozymes and their applications

X Zhang, S Lin, S Liu, X Tan, Y Dai, F Xia - Coordination Chemistry …, 2021 - Elsevier
Nanozymes, the next-generation artificial enzymes, are nanomaterials with enzyme-like
characteristics and have been widely used in detection, disease diagnosis, biological …

Synthesis, catalytic properties and application in biosensorics of nanozymes and electronanocatalysts: A review

N Stasyuk, O Smutok, O Demkiv, T Prokopiv, G Gayda… - Sensors, 2020 - mdpi.com
The current review is devoted to nanozymes, ie, nanostructured artificial enzymes which
mimic the catalytic properties of natural enzymes. Use of the term “nanozyme” in the …

Bioorthogonal nanozymes for breast cancer imaging and therapy

X Zhang, Y Liu, J Doungchawee… - Journal of Controlled …, 2023 - Elsevier
Bioorthogonal catalysis via transition metal catalysts (TMCs) enables the generation of
therapeutics locally through chemical reactions not accessible by biological systems. This …

Thermally gated bio-orthogonal nanozymes with supramolecularly confined porphyrin catalysts for antimicrobial uses

R Cao-Milán, S Gopalakrishnan, LD He, R Huang… - Chem, 2020 - cell.com
Bio-orthogonal catalysis has the capability of localized generation of imaging and
therapeutic molecules in vitro and in vivo. The integration of these catalysts into …

Macrophage-encapsulated bioorthogonal nanozymes for targeting cancer cells

R Das, J Hardie, BP Joshi, X Zhang, A Gupta… - JACS Au, 2022 - ACS Publications
Macrophages migrate to tumor sites by following chemoattractant gradients secreted by
tumor cells, providing a truly active targeting strategy for cancer therapy. However …