Gastrin and cholecystokinin (CCK) are two of the oldest hormones and within the past 15
years there has been an exponential increase in knowledge of their pharmacology, cell …

This review describes the recent advances in the microwave-assisted synthesis of 7-
membered and larger heterocyclic compounds. Several types of reaction for the cyclization …

US8664229B2 - Heterocyclic compounds as pesticides - Google Patents US8664229B2 -
Heterocyclic compounds as pesticides - Google Patents Heterocyclic compounds as …

CA 2095, 967 11, 1993 CA 2671 179 A1 6, 2008 CA 273O844 A1 1, 2010 DE 100 14 006
A1 9, 2001 EP O 482 349 A2 4f1992 EP O 539 588 A1 5, 1993 EP O 569810 A1 11, 1993 …

Urotensin II receptor (UT) modulators that differentiate the effects of the endogenous cyclic
peptide ligands urotensin II (UII) and urotensin II-related peptide (URP) offer potential for …

The Mg2+-dependent Mycobacterium tuberculosis salicylate synthase (MbtI) is a key
enzyme involved in the biosynthesis of siderophores. Because iron is essential for the …

A method for the direct arylation of benzotriazepines is reported, employing an aryl iodide as
the coupling partner, copper iodide as the catalyst, and lithium tert-butoxide as the base. A …

1, 4-benzodiazepin-2-ones have applications in many areas of medicinal chemistry that are
not restricted to 'classical'CNS treatments such as sedatives, epilepsy and muscle relaxants …

A Brønsted acid-catalyzed α-C (sp3)–H amination of cyclic amines using hydrazines as
coupling partners has been reported. This methodology provides a unique protocol to the …

A series of benzimidazolium chlorides was synthesized as precursors to N-heterocyclic
carbene ligands, with N-substituents varying in size from 3, 5-xylyl (1a) to first-generation …