Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors

T Meyerrose, S Olson, S Pontow, S Kalomoiris… - Advanced drug delivery …, 2010 - Elsevier
Mesenchymal stem cells (MSC) are a promising tool for cell therapy, either through direct
contribution to the repair of bone, tendon and cartilage or as an adjunct therapy through …

Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer.

RE Donahue, SW Kessler, D Bodine… - The Journal of …, 1992 - rupress.org
Moloney Murine Leukemia Virus (MoMuLV) causes T cell neoplasms in rodents but is not
known to be a pathogen in primates. The core protein and enzyme genes of the MoMuLV …

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus …

RK Akkina, RM Walton, ML Chen, QX Li… - Journal of …, 1996 - Am Soc Microbiol
Currently, amphotropic retroviral vectors are widely used for gene transfer into CD34+
hematopoietic progenitor cells. The relatively low levels of transduction efficiency associated …

Leukemia inhibitory factor: part of a large ingathering family

JL Taupin, V Pitard, J Dechanet, V Miossec… - International reviews …, 1998 - Taylor & Francis
Leukemia Inhibitory Factor (LIF) has a wide variety of biological activities. It regulates the
differentiation of embryonic stem cells, neural cells, osteoblasts, adipocytes, hepatocytes …

Engraftment in Nonobese Diabetic Severe Combined Immunodeficient Mice of Human CD34+ Cord Blood Cells After Ex Vivo Expansion: Evidence for the …

W Piacibello, F Sanavio, A Severino… - Blood, The Journal …, 1999 - ashpublications.org
Understanding the repopulating characteristics of human hematopoietic stem/progenitor
cells is crucial for predicting their performance after transplant into patients receiving high …

Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation

CE Dunbar, M Cottler-Fox, JA O'Shaughnessy, S Doren… - 1995 - ashpublications.org
We report here on a preliminary human autologous transplantation study of retroviral gene
transfer to bone marrow (BM) and peripheral blood (PB)-derived CD34-enriched cells …

[图书][B] Biomedical technology and devices handbook

G Zouridakis - 2003 - taylorfrancis.com
Concise yet comprehensive, the Biomedical Technology and Devices Handbook illuminates
the equipment, devices, and techniques used in modern medicine to diagnose, treat, and …

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

R Abonour, DA Williams, L Einhorn, KM Hall, J Chen… - Nature medicine, 2000 - nature.com
Pre-clinical studies indicate that efficient retrovirus-mediated gene transfer into
hematopoietic stem cells and progenitor cells can be achieved by co-localizing retroviral …

Adhesion to fibronectin maintains regenerative capacity during ex vivo culture and transduction of human hematopoietic stem and progenitor cells

MA Dao, K Hashino, I Kato… - Blood, The Journal of the …, 1998 - ashpublications.org
Recent reports have indicated that there is poor engraftment from hematopoietic stem cells
(HSC) that have traversed cell cycle ex vivo. However, inducing cells to cycle in culture is …

Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of …

JA Nolta, MB Hanley, DB Kohn - 1994 - ashpublications.org
We have developed a novel cotransplantation system in which gene-transduced human
CD34+ progenitor cells are transplanted into immunodeficient (bnx) mice together with …