Simultaneous quantification of gymnemic acid as gymnemagenin and charantin as β-sitosterol using validated HPTLC densitometric method

J Ahamad, S Amin, SR Mir - Journal of chromatographic science, 2015 - academic.oup.com
Gymnemic acid and charantin are well-established antidiabetic phytosterols found in
Gymnema sylvestre and Momordica charantia, respectively. The fact that these plants are …

Assessment of diversity amongst natural populations of Gymnema sylvestre from India and development of a validated HPLC protocol for identification and …

T Dhanani, R Singh, A Waman, P Patel… - Industrial Crops and …, 2015 - Elsevier
In order to supply uniform, genuine, good quality raw material to the pharmaceutical
industries and to reduce the burden on natural stocks, cultivation of medicinal crops is the …

[PDF][PDF] Determination of gymnemic acid level in Gymnema inodorum leaves using multiple reaction monitoring mass spectrometry

W Srinuanchai, R Nooin, S Jarussophon… - J. Chem. Metrol, 2019 - acgpubs.org
The samples of G. inodorum leaves (GI1, GI2, GI3 and GI4) were gently cleaned with water
and dried in a hot-air oven at 60 C for 24 hours. The dried leaves were ground into a powder …

Green and proficient process for industrial-scale preparation of Gymnema sylvestre standardized-extract enriched with Gymnemic acids through polymer-matrix …

D Kumar, VK Singh, NP Yadav, S Tandon… - Journal of Industrial and …, 2022 - Elsevier
Gymnema sylvestre is an important medicinal plant, but a method for preparing standardized
extract enriched with biomarkers is not available. The practiced crude hydro-alcoholic …

In vitro metabolic stability and permeability of Gymnemagenin and its in vivo pharmacokinetic correlation in rats–a pilot study

R Bera, A Kundu, T Sen, D Adhikari… - Planta medica, 2016 - thieme-connect.com
Gymnema sylvestre is traditionally used for diabetes mellitus. A literature survey revealed
very few reports, particularly on rat liver microsomal stability, caco-2 permeability and efflux …

Insight into the morphological and bioactive variability in the ex-situ genepool of Gymnema sylvestre accessions collected from Peninsular India

MR Rohini, HC Raghavendra, VK Rao… - Genetic Resources and …, 2024 - Springer
Abstract Gymnema sylvestre (Retz.) R. Br. ex Sm.(Gudmar) is a medicinal crop that is highly
valued because of its antidiabetic and diverse therapeutic properties. In this study, 35 …

Quantitative Estimation of Gymnemagenin in Gymnema sylvestre Extract and its Marketed Formulations using the HPLC–ESI–MS/MS Method

B Kamble, A Gupta, D Patil, S Janrao… - Phytochemical …, 2013 - Wiley Online Library
Introduction Gymnema sylvestre, with gymnemic acids as active pharmacological
constituents, is a popular ayurvedic herb and has been used to treat diabetes, as a remedy …

Extraction efficacy, stability assessment and seasonal variation of bioactive 'gymnemagenin'in Gymnema sylvestre

N Manika, S Singh, RK Verma, GD Bagchi - Industrial Crops and Products, 2013 - Elsevier
Gymnema sylvestre (Asclepiadaceae) is a highly valued medicinal plant and being used
nowadays in many poly-herbal formulations due to its potential antidiabetic activity and other …

Chemical variability in gymnemagenin, deacyl gymnemic acid, lupeol and stigmasterol of Gymnema sylvestre R. Br. populations in India

S Rastogi, MM Pandey, K Vaishnav… - Indian Journal of …, 2023 - op.niscpr.res.in
Variability in chemical composition of Gymnema sylvestre R. Br.(Apocynaceae) sampled
from different bio-geographical regions of India was investigated. The impact of geographic …

Development and validation of a HPTLC method for simultaneous densitometric analysis of gymnemagenin and 18β-glycyrrhetinic acid in herbal drug formulation.

SE Potawale, SY Gabhe, KR Mahadik - 2012 - cabidigitallibrary.org
A new, simple high performance thin layer chromatographic (HPTLC) method for
simultaneous determination of gymnemagenin and 18β-glycyrrhetinic acid in herbal drug …