Tumor metastasis is a multistep process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. Metastasis occurs through a series of steps …

Review covering up to 07/2019 (−)-Parthenolide is a germacrane sesquiterpene lactone,
available in ample amounts from the traditional medical plant feverfew (Tanacetum …

Cell migration on planar surfaces is driven by cycles of actin protrusion, integrin-mediated
adhesion, and myosin-mediated contraction; however, this mechanism may not accurately …

Postmitotic neurons require persistently active controls to maintain terminal differentiation.
Unlike dividing cells, aberrant cell cycle activation in mature neurons causes apoptosis …

The number of known pathologies involving deregulated Tau expression/metabolism is
increasing. Indeed, in addition to tauopathies, which comprise approximately 30 diseases …

Metastatic cases of breast cancer pose the primary challenge in clinical management of this
disease, demanding the identification of effective therapeutic strategies that remain wanting …

Epithelial-to-mesenchymal transition (EMT) is associated with increased breast tumor
metastasis; however, the specific mechanisms by which EMT promotes metastasis remain …

The structure and mechanics of many connective tissues are dictated by a collagen-rich
extracellular matrix (ECM), where collagen fibers provide topological cues that direct cell …

The tumor microenvironment determines development and progression of many cancers.
Epithelial–mesenchymal transition (EMT) is fundamental to tumor progression and …

Abstract Introduction The cytochrome P450 (CYP) enzymes are a class of heme-containing
enzymes involved in phase I metabolism of a large number of xenobiotics. The CYP family …