Preeclampsia, a hypertensive disorder peculiar to pregnancy, is a systemic syndrome that
appears to originate in the placenta and is characterized by widespread maternal …

Human pregnancy is characterized by insulin resistance, traditionally attributed to the effects
of placental hormones. Normal pregnancy—induced insulin resistance is further enhanced …

Objective: Preeclampsia (PE) has been classified into early-and late-onset disease. These
two phenotypic variants of PE have been proposed to have a different pathophysiology …

Adipocytokines are hormonally active molecules that are believed to play a key role in the
regulation of crucial biological processes in the human body. Numerous experimental …

Objective: An imbalance between maternal angiogenic/anti-angiogenic factors
concentrations has been observed in preeclampsia (PE) and other obstetrical syndromes …

Objective: To determine whether maternal plasma concentrations of placental growth factor
(PlGF), soluble endoglin (sEng), soluble vascular endothelial growth factor receptor-1 …

Preeclampsia is not fully understood; and few biomarkers, therapeutic targets, and
therapeutic agents for its management have been identified. Original investigative findings …

Objective: Adipose tissue has now emerged as a powerful endocrine organ via the
production of adipokines. Visfatin, a novel adipokine with diabetogenic and immuno …

Adiponectin is the most abundant protein secreted by the white adipose tissue. It circulates
at high levels in the bloodstream and its serum concentration is inversely correlated with …

Objective: Dysregulation of maternal circulating adipokines has been implicated in several
“great obstetrical syndromes” including preeclampsia (PE), small-for-gestational age (SGA) …