Snake venom components: tools and cures to target cardiovascular diseases
Cardiovascular diseases (CVDs) are considered as a major cause of death worldwide.
Therefore, identifying and developing therapeutic strategies to treat and reduce the …
Therefore, identifying and developing therapeutic strategies to treat and reduce the …
Inflammatory Effects of Bothrops Phospholipases A2: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation
V Moreira, E Leiguez, PM Janovits, R Maia-Marques… - Toxins, 2021 - mdpi.com
Phospholipases A2s (PLA2s) constitute one of the major protein groups present in the
venoms of viperid and crotalid snakes. Snake venom PLA2s (svPLA2s) exhibit a remarkable …
venoms of viperid and crotalid snakes. Snake venom PLA2s (svPLA2s) exhibit a remarkable …
Experimental Bothrops atrox Envenomation: Blood Plasma Proteome Effects after Local Tissue Damage and Perspectives on Thromboinflammation
JS Cavalcante, IMC Brito, LA De Oliveira, LC De Barros… - Toxins, 2022 - mdpi.com
The clinical manifestations of Bothrops atrox envenoming involve local and systemic
changes, among which edema requires substantial attention due to its ability to progress to …
changes, among which edema requires substantial attention due to its ability to progress to …
A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice
J dos Santos Cavalcante, CAS de Almeida… - Journal of …, 2022 - Elsevier
Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and
complex pathophysiological condition. Bothrops leucurus is the main species of medical …
complex pathophysiological condition. Bothrops leucurus is the main species of medical …
PPARs in Clinical Experimental Medicine after 35 Years of Worldwide Scientific Investigations and Medical Experiments
A Skoczyńska, M Ołdakowska, A Dobosz, R Adamiec… - Biomolecules, 2024 - mdpi.com
This year marks the 35th anniversary of Professor Walter Wahli's discovery of the PPARs
(Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark …
(Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark …
A Representative GIIA Phospholipase A2 Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development
E Leiguez, P Motta, R Maia Marques, B Lomonte… - Biomolecules, 2020 - mdpi.com
Adipose tissue secretes proinflammatory mediators which promote systemic and adipose
tissue inflammation seen in obesity. Group IIA (GIIA)-secreted phospholipase A2 (sPLA2) …
tissue inflammation seen in obesity. Group IIA (GIIA)-secreted phospholipase A2 (sPLA2) …
[HTML][HTML] Identification of cross-reactive human single-chain variable fragments against phospholipases A2 from Lachesis muta and Bothrops spp venoms
LB Campos, MB Pucca, LC Silva, G Pessenda… - Toxicon, 2020 - Elsevier
Bushmasters (Lachesis spp) and lancehead vipers (Bothrops spp) are two of the most
dangerous snakes found in Latin America. Victims of envenoming by these snakes require …
dangerous snakes found in Latin America. Victims of envenoming by these snakes require …
Instituto Butantan and Instituto Clodomiro Picado: A long-standing partnership in science, technology, and public health
JM Gutiérrez, CFP Teixeira, HW Fan - Toxicon, 2021 - Elsevier
Instituto Butantan (São Paulo, Brazil) and Instituto Clodomiro Picado (San José, Costa Rica)
are public institutions devoted to scientific and technological research, production of …
are public institutions devoted to scientific and technological research, production of …