Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …

Cancer cell possesses numerous adaptations to resist the immune system response and
chemotherapy. One of the most significant properties of the neoplastic cells is the altered …

The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …

The acquisition of genetic alterations, clonal evolution, and the tumor microenvironment
promote cancer progression, metastasis and therapy resistance. These events correspond …

Globally, breast cancer is the most common cancer type and is one of the most significant
causes of deaths in women. To date, multiple clinical interventions have been applied …

The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, also known
as statins, are administered as first-line therapy for hypercholesterolemia, both as primary …

Breast cancer is the most prevalent type of tumor and the second leading cause of death
due to cancer among women. Although screening methods, diagnosis and therapeutic …

Background Breast cancer is the second most common cause of cancer-related death
among women. Advances in our understanding of the disease have translated into better …

Breast cancer is the most common invasive tumor in women and the second leading cause
of cancer-related death. Nanomedicine raises high expectations for millions of patients as it …

Statins have been shown to inhibit cell proliferation in vitro and tumor growth in animal
models. Various studies have also shown a decreased cancer-specific mortality rate in …