Reflectance confocal microscopy of skin in vivo: From bench to bedside

M Rajadhyaksha, A Marghoob, A Rossi… - Lasers in surgery …, 2017 - Wiley Online Library
Following more than two decades of effort, reflectance confocal microscopy (RCM) imaging
of skin was granted codes for reimbursement by the US Centers for Medicare and Medicaid …

Reflectance Confocal Microscopy for In Vivo Skin Imaging

P Calzavara‐Pinton, C Longo… - Photochemistry and …, 2008 - Wiley Online Library
Reflectance confocal microscopy (RCM) is a novel noninvasive technique for “in vivo”
examination of the skin. In a confocal microscope, near‐infrared light from a diode laser is …

Line-field confocal optical coherence tomography for high-resolution noninvasive imaging of skin tumors

A Dubois, O Levecq, H Azimani, D Siret… - … of biomedical optics, 2018 - spiedigitallibrary.org
An optical technique called line-field confocal optical coherence tomography (LC-OCT) is
introduced for high-resolution, noninvasive imaging of human skin in vivo. LC-OCT …

NKp46 receptor-mediated interferon-γ production by natural killer cells increases fibronectin 1 to alter tumor architecture and control metastasis

A Glasner, A Levi, J Enk, B Isaacson, S Viukov… - Immunity, 2018 - cell.com
Natural killer (NK) cells are innate lymphoid cells, and their presence within human tumors
correlates with better prognosis. However, the mechanisms by which NK cells control tumors …

Effect of reflectance confocal microscopy for suspect lesions on diagnostic accuracy in melanoma: a randomized clinical trial

G Pellacani, F Farnetani, S Ciardo, J Chester… - JAMA …, 2022 - jamanetwork.com
Importance Previous systematic reviews and meta-analyses have concluded that given data
paucity, a comparison of reflectance confocal microscopy (RCM) with dermoscopy is …

[HTML][HTML] The impact of in vivo reflectance confocal microscopy on the diagnostic accuracy of lentigo maligna and equivocal pigmented and nonpigmented macules of …

P Guitera, G Pellacani, KA Crotty, RA Scolyer… - Journal of Investigative …, 2010 - Elsevier
Limited studies have reported the in vivo reflectance confocal microscopy (RCM) features of
lentigo maligna (LM). A total of 64 RCM features were scored retrospectively and blinded to …

[HTML][HTML] In vivo confocal microscopy for diagnosis of melanoma and basal cell carcinoma using a two-step method: analysis of 710 consecutive clinically equivocal …

P Guitera, SW Menzies, C Longo, AM Cesinaro… - Journal of investigative …, 2012 - Elsevier
We describe two algorithms to diagnose basal cell carcinomas (BCCs) and melanomas
(MMs) using in vivo reflectance confocal microscopy (RCM). A total of 710 consecutive …

Reflectance confocal microscopy as a second‐level examination in skin oncology improves diagnostic accuracy and saves unnecessary excisions: a longitudinal …

G Pellacani, P Pepe, A Casari… - British Journal of …, 2014 - academic.oup.com
Background Dermatoscopy increases both the sensitivity and specificity of melanoma
diagnosis. Reflectance confocal microscopy (RCM) is a noninvasive technique that …

Optical radiomic signatures derived from optical coherence tomography images improve identification of melanoma

Z Turani, E Fatemizadeh, T Blumetti, S Daveluy… - Cancer research, 2019 - AACR
The current gold standard for clinical diagnosis of melanoma is excisional biopsy and
histopathologic analysis. Approximately 15–30 benign lesions are biopsied to diagnose …

Impact of in vivo reflectance confocal microscopy on the number needed to treat melanoma in doubtful lesions

I Alarcon, C Carrera, J Palou, L Alos… - British journal of …, 2014 - academic.oup.com
Background The number needed to treat (NNT) ratio is an effective method for measuring
accuracy in melanoma detection. Dermoscopy reduces the number of false positives and …