Low-voltage myocardium-guided ablation trial of persistent atrial fibrillation

Y Huo, T Gaspar, R Schönbauer, M Wójcik… - NEJM …, 2022 - evidence.nejm.org
Background Clinically effective ablation approaches for patients with persistent atrial
fibrillation (AF) are still being debated. So far, ablation targets and strategies beyond …

Ablation strategies for intramural ventricular arrhythmias

V Neira, P Santangeli, P Futyma, J Sapp… - Heart Rhythm, 2020 - Elsevier
Intramural origin of ventricular arrhythmias is one of the reasons for failure of catheter
ablation, especially in nonischemic substrates. Conventional unipolar ablation has limited …

Radiofrequency ablation to achieve durable pulmonary vein isolation

MJ Mulder, MJB Kemme, CP Allaart - EP Europace, 2022 - academic.oup.com
Pulmonary vein isolation (PVI) by radiofrequency (RF) ablation is an important alternative to
antiarrhythmic drugs in the treatment of symptomatic atrial fibrillation. However, the inability …

Pulsed field ablation of left ventricular myocardium in a swine infarct model

SI Im, S Higuchi, A Lee, C Stillson, E Buck… - Clinical …, 2022 - jacc.org
Background Pulsed field ablation (PFA) leads to cell death by irreversible electroporation.
There are limited data about PFA lesion characteristics in the ventricle, particularly in the …

Effect of pulsed-field and radiofrequency ablation on heterogeneous ventricular scar in a swine model of healed myocardial infarction

A Younis, I Zilberman, A Krywanczyk… - Circulation …, 2022 - Am Heart Assoc
Background: Pulsed-field ablation (PFA) is a nonthermal energy with higher selectivity to
myocardial tissue in comparison to radiofrequency ablation (RFA). We compared the effects …

Electrophysiology, pathology, and imaging of pulsed field ablation of scarred and healthy ventricles in swine

I Kawamura, VY Reddy… - Circulation …, 2023 - Am Heart Assoc
Background: Pulsed field ablation (PFA) has recently been shown to penetrate ischemic
scar, but details on its efficacy, risk of arrhythmias, and imaging insights are lacking. In a …

In vivo pulsed-field ablation in healthy vs. chronically infarcted ventricular myocardium: biophysical and histologic characterization

U Sandhu, L Alkukhun, B Kheiri, J Hodovan… - Europace, 2023 - academic.oup.com
Aims Data on ventricular pulsed-field ablation (PFA) are sparse in the setting of chronic
myocardial infarction (MI). The objective of this study was to compare the biophysical and …

Anatomic approach with bipolar ablation between the left pulmonic cusp and left ventricular outflow tract for left ventricular summit arrhythmias

P Futyma, P Santangeli, H Pürerfellner, NV Pothineni… - Heart Rhythm, 2020 - Elsevier
Background Radiofrequency catheter ablation (RFCA) of ventricular arrhythmias (VAs)
arising from the inaccessible basal region of the left ventricular summit (LVS) is challenging …

Evaluation of radiofrequency ablation irrigation type: in vivo comparison of normal versus half-normal saline lesion characteristics

CM Tschabrunn, NVK Pothineni, WH Sauer… - Clinical …, 2020 - jacc.org
Objectives This study investigated the impact of the type of catheter irrigant used during
delivery of radiofrequency ablation. Background The use of half-normal saline (HNS) as an …

Utility and limitations of ablation index for guiding therapy in ventricular myocardium

A Younis, I Zilberman, H Yavin, K Higuchi… - Clinical …, 2023 - jacc.org
Background Ablation index (AI) is used for guiding therapy during pulmonary vein isolation.
However, its potential utility in ventricular myocardium is unknown. Objectives This study …