Abstract Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules
that are ubiquitous across species ranging from viruses to mammals. Important advances …

In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …

Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is
complex and entails coagulation dysfunction, inflammation, and immune disorders …

Noncoding RNA (ncRNA) transcripts that did not code proteins but regulate their functions
were extensively studied for the last two decades and the plethora of discoveries have …

Abstract Background Circular RNAs (circRNAs) mediate the infiltration of tumor-associated
macrophages (TAMs) to facilitate carcinogenesis and development of various types of …

Background Circular RNA (circRNA) has been implicated in various diseases; however, its
role in atopic dermatitis (AD) or psoriasis remains unclear. Objective We sought to determine …

Abstract Background Circular RNA (circRNA) is a novel class noncoding RNA (ncRNA) that
plays a critical role in various cancers, including prostate cancer (PCa). However, the clinical …

The immune microenvironment plays a critical role in regulating skin wound healing.
Macrophages, the main component of infiltrating inflammatory cells, play a pivotal role in …

Osteoarthritis (OA) is a common degenerative joint disease that can lead to disability.
Blocking the complex malignant feedback loop system dominated by oxidative stress and …