Polymers play important roles in the design of delivery nanocarriers for cancer therapies.
Polymeric nanocarriers with anticancer drugs conjugated or encapsulated, also known as …

Introduction: We discuss chemical conjugation strategies for antibody-drug conjugates
(ADCs) from an industrial perspective and compare three promising chemical conjugation …

Antibody–drug conjugates (ADC) are an emerging drug class that uses antibodies to
improve cytotoxic drug targeting for cancer treatment. ADCs in current clinical trials achieve …

ELPs are genetically engineered, thermally responsive polypeptides that preferentially
accumulate in solid tumors subjected to focused, mild hyperthermia. In this paper, we report …

Drug delivery systems (DDSs) are of paramount importance to deliver drugs at the intended
targets, eg, tumor cells or tissue by prolonging blood circulation and optimizing the …

The design and synthesis of a family of cationic, pH-sensitive poly (amidoamine) s are
reported. Acetal or ketal linkages were incorporated into the backbone of the polymers to …

New amphiphilic star-shaped architectures with dense hydrophilic shells were synthesized
by a combination of ring-opening polymerization (ROP) of ε-caprolactone (CL) and atom …

A biodegradable brush-type copolymer PHF-g-(PCL-PEG) based on a cleavable polyacetal
backbone and biodegradable side chain modified with polyethylene glycol (PEG) was …

Abstract Poly (ethylene glycol)(PEG)–protein therapeutics exhibit enhanced
pharmacokinetics, but have drawbacks including decreased protein activities and polymer …

Proteins represent a versatile biopolymer material for the preparation of nanoparticles. For
drug delivery applications an acid-triggered disassembly and payload release is preferred …