Leptospirosis: a zoonotic disease of global importance

AR Bharti, JE Nally, JN Ricaldi, MA Matthias… - The Lancet infectious …, 2003 - thelancet.com
In the past decade, leptospirosis has emerged as a globally important infectious disease. It
occurs in urban environments of industrialised and developing countries, as well as in rural …

Rats, cities, people, and pathogens: a systematic review and narrative synthesis of literature regarding the ecology of rat-associated zoonoses in urban centers

CG Himsworth, KL Parsons, C Jardine… - Vector-Borne and …, 2013 - liebertpub.com
Urban Norway and black rats (Rattus norvegicus and Rattus rattus) are the source of a
number of pathogens responsible for significant human morbidity and mortality in cities …

Actionable diagnosis of neuroleptospirosis by next-generation sequencing

MR Wilson, SN Naccache, E Samayoa… - … England Journal of …, 2014 - Mass Medical Soc
A 14-year-old boy with severe combined immunodeficiency presented three times to a
medical facility over a period of 4 months with fever and headache that progressed to …

Urban epidemic of severe leptospirosis in Brazil

AI Ko, MG Reis, CMR Dourado, WD Johnson, LW Riley - The Lancet, 1999 - thelancet.com
Background Leptospirosis has, traditionally, been considered a sporadic rural disease. We
describe a large urban outbreak of leptospirosis. Methods Active surveillance for …

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

C Werts, RI Tapping, JC Mathison, TH Chuang… - Nature …, 2001 - nature.com
Leptospira interrogans are zoonotic pathogens that have been linked to a recent increased
incidence of morbidity and mortality in highly populated tropical urban centers. They are …

Leptospirosis in the Asia Pacific region

AFB Victoriano, LD Smythe, N Gloriani-Barzaga… - BMC infectious …, 2009 - Springer
Background Leptospirosis is a worldwide zoonotic infection that has been recognized for
decades, but the problem of the disease has not been fully addressed, particularly in …

An overview of anthropogenic actions as drivers for emerging and re-emerging zoonotic diseases

SS Tazerji, R Nardini, M Safdar, AA Shehata… - Pathogens, 2022 - mdpi.com
Population growth and industrialization have led to a race for greater food and supply
productivity. As a result, the occupation and population of forest areas, contact with wildlife …

[HTML][HTML] Neglected infections of poverty in the United States of America

PJ Hotez - PLoS neglected tropical diseases, 2008 - journals.plos.org
In the United States, there is a largely hidden burden of diseases caused by a group of
chronic and debilitating parasitic, bacterial, and congenital infections known as the …

[图书][B] Hepatology Principles and Practice: History· Morphology Biochemistry· Diagnostics Clinic· Therapy

E Kuntz - 2006 - Springer
Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

[HTML][HTML] Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans

R Plank, D Dean - Microbes and infection, 2000 - Elsevier
Leptospirosis is probably the world′ s most widespread zoonosis. It remains
underdiagnosed largely due to the broad spectrum of signs and symptoms attributable to …