Introduction Poor or inconsistent adherence to daily oral pre-exposure prophylaxis (PrEP)
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …

The human immunodeficiency virus (HIV) remains a global health concern, with 37.7 million
people currently living with the infection and 1.5 million new cases every year. Current …

Pancreatic islet transplantation efficacy for type 1 diabetes (T1D) management is limited by
hypoxia-related graft attrition and need for systemic immunosuppression. To overcome …

Despite extensive research investment, malignant brain tumors continue to be associated
with significant morbidity and mortality. Implantable microdevices placed directly in the …

The impact of pre-exposure prophylaxis (PrEP) on slowing the global HIV epidemic hinges
on effective drugs and delivery platforms. Oral drug regimens are the pillar of HIV PrEP, but …

Cancer vaccines harness the host immune system to generate antigen-specific antitumor
immunity for long-term tumor elimination with durable immunomodulation. Commonly …

Agonist CD40 monoclonal antibodies (mAb) is a promising immunotherapeutic agent for
cold‐to‐hot tumor immune microenvironment (TIME) conversion. Pancreatic ductal …

Abstract Treatment nonadherence is a pressing issue in people living with HIV (PLWH), as
they require lifelong therapy to maintain viral suppression. Poor adherence leads to …

Interstitial fluid (IF) is pivotal in maintaining balance within tissues and organs, facilitating
molecular transport and supporting homeostasis. Various drug delivery systems, such as …

Automated drug delivery systems (ADDS) improve chronic disease management by
enhancing adherence and reducing patient burden, particularly in conditions like type 1 …