Cerebral plasticity: Windows of opportunity in the developing brain
Background Neuroplasticity refers to the inherently dynamic biological capacity of the central
nervous system (CNS) to undergo maturation, change structurally and functionally in …
nervous system (CNS) to undergo maturation, change structurally and functionally in …
Development and arealization of the cerebral cortex
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …
order cognitive functions. How this regional diversity develops from an initially uniform …
Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex?
DJ Piekarski, CM Johnson, JR Boivin, AW Thomas… - Brain research, 2017 - Elsevier
Postnatal brain development is studded with sensitive periods during which experience
dependent plasticity is enhanced. This enables rapid learning from environmental inputs …
dependent plasticity is enhanced. This enables rapid learning from environmental inputs …
Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons
Inhibitory neurons regulate the adaptation of neural circuits to sensory experience, but the
molecular mechanisms by which experience controls the connectivity between different …
molecular mechanisms by which experience controls the connectivity between different …
Neuronal replacement therapy: previous achievements and challenges ahead
S Grade, M Götz - NPJ Regenerative medicine, 2017 - nature.com
Lifelong neurogenesis and incorporation of newborn neurons into mature neuronal circuits
operates in specialized niches of the mammalian brain and serves as role model for …
operates in specialized niches of the mammalian brain and serves as role model for …
Parvalbumin-positive interneurons regulate cortical sensory plasticity in adulthood and development through shared mechanisms
Parvalbumin-positive neurons are the largest class of GABAergic, inhibitory neurons in the
central nervous system. In the cortex, these fast-spiking cells provide feedforward and …
central nervous system. In the cortex, these fast-spiking cells provide feedforward and …
Neuregulin-1/ErbB4 signaling regulates visual cortical plasticity
Experience alters cortical networks through neural plasticity mechanisms. During a
developmental critical period, the most dramatic consequence of occluding vision through …
developmental critical period, the most dramatic consequence of occluding vision through …
Paradoxical motor recovery from a first stroke after induction of a second stroke: reopening a postischemic sensitive period
SR Zeiler, R Hubbard, EM Gibson… - … and neural repair, 2016 - journals.sagepub.com
Background and objective. Prior studies have suggested that after stroke there is a time-
limited period of increased responsiveness to training as a result of heightened plasticity—a …
limited period of increased responsiveness to training as a result of heightened plasticity—a …
Therapeutic potential of astrocyte transplantation
N Hastings, WL Kuan, A Osborne… - Cell …, 2022 - journals.sagepub.com
Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …
Are critical periods reversible in the adult brain? Insights on cortical specializations based on sensory deprivation studies
We review here studies with visual and auditory deprived/recovery populations to argue for
the need of a redefinition of the crucial role of unisensory-specific experiences during critical …
the need of a redefinition of the crucial role of unisensory-specific experiences during critical …