Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an
essential element of bacterial biology. Efforts to understand the Mycobacterium tuberculosis …

The human gut microbiota is a key contributor to host metabolism and physiology, thereby
impacting in various ways on host health. This complex microbial community has developed …

Mycobacterium tuberculosis synthesizes intra-and extracellular α-glucans that were
believed to originate from separate pathways. The extracellular glucose polymer is the main …

This review commemorates the 50th anniversary of the Nobel Prize in Chemistry awarded to
Luis F. Leloir 'for his discovery of sugar-nucleotides and their role in the biosynthesis of …

Protein production using recombinant DNA technology has a fundamental impact on our
understanding of biology through providing proteins for structural and functional studies …

Bacteria have acquired sophisticated mechanisms for assembling and disassembling
polysaccharides of different chemistry. α-d-Glucose homopolysaccharides, so-called α …

Glucan-branching enzyme plays an essential role in the formation of branched
polysaccharides, glycogen, and amylopectin. Only one type of branching enzyme, belonging …

Trehalose biosynthesis is considered an attractive target for the development of
antimicrobials against fungal, helminthic and bacterial pathogens including Mycobacterium …

It has long been reported that Mycobacterium tuberculosis is capable of synthesizing the α-
glucan glycogen. However, what makes this bacterium stand out is that it coats itself in a …

We explored the ability of ADP-glucose pyrophosphorylase (ADP-Glc PPase) from different
bacteria to use glucosamine (GlcN) metabolites as a substrate or allosteric effectors. The …