Genome-scale metabolic modeling enables in-depth understanding of big data

A Passi, JD Tibocha-Bonilla, M Kumar, D Tec-Campos… - Metabolites, 2021 - mdpi.com
Genome-scale metabolic models (GEMs) enable the mathematical simulation of the
metabolism of archaea, bacteria, and eukaryotic organisms. GEMs quantitatively define a …

Metabolomics and complementary techniques to investigate the plant phytochemical cosmos

H Tsugawa, A Rai, K Saito, R Nakabayashi - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …

The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants …

SMD Seaver, F Liu, Q Zhang, J Jeffryes… - Nucleic acids …, 2021 - academic.oup.com
For over 10 years, ModelSEED has been a primary resource for the construction of draft
genome-scale metabolic models based on annotated microbial or plant genomes. Now …

Systematic multi-omics integration (MOI) approach in plant systems biology

IN Jamil, J Remali, KA Azizan… - Frontiers in plant …, 2020 - frontiersin.org
Across all facets of biology, the rapid progress in high-throughput data generation has
enabled us to perform multi-omics systems biology research. Transcriptomics, proteomics …

High-throughput plant phenotyping: a role for metabolomics?

RD Hall, JC D'Auria, ACS Ferreira, Y Gibon… - Trends in Plant …, 2022 - cell.com
High-throughput (HTP) plant phenotyping approaches are developing rapidly and are
already helping to bridge the genotype–phenotype gap. However, technologies should be …

Plant and algal lipidomes: Analysis, composition, and their societal significance

J Jouhet, E Alves, Y Boutté, S Darnet… - Progress in Lipid …, 2024 - Elsevier
Plants and algae play a crucial role in the earth's ecosystems. Through photosynthesis they
convert light energy into chemical energy, capture CO2 and produce oxygen and energy …

Life at the borderlands: microbiomes of interfaces critical to One Health

SR Law, F Mathes, AM Paten… - FEMS Microbiology …, 2024 - academic.oup.com
Microbiomes are foundational components of the environment that provide essential
services relating to food security, carbon sequestration, human health, and the overall well …

Elucidating plant-microbe-environment interactions through omics-enabled metabolic modelling using synthetic communities

AE Beck, M Kleiner, AK Garrell - Frontiers in Plant Science, 2022 - frontiersin.org
With a growing world population and increasing frequency of climate disturbance events, we
are in dire need of methods to improve plant productivity, resilience, and resistance to both …

Unraveling the genome of a high yielding Colombian sugarcane hybrid

JH Trujillo-Montenegro… - Frontiers in Plant …, 2021 - frontiersin.org
Recent developments in High Throughput Sequencing (HTS) technologies and
bioinformatics, including improved read lengths and genome assemblers allow the …

Advances in genome-scale metabolic modeling toward microbial community analysis of the human microbiome

E Esvap, KO Ulgen - ACS Synthetic Biology, 2021 - ACS Publications
A genome-scale metabolic model (GEM) represents metabolic pathways of an organism in a
mathematical form and can be built using biochemistry and genome annotation data. GEMs …