Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay

I Neefs, N De Meulenaere, T Vanpoucke… - Molecular …, 2024 - Wiley Online Library
DNA methylation biomarkers have emerged as promising tools for cancer detection.
Common methylation patterns across tumor types allow multi‐cancer detection. Droplet …

[HTML][HTML] EGFR mutation testing from pleural effusions of non-small cell lung cancer patients at the institute for oncology and radiology of Serbia

M Vukovic, M Tanic, A Damjanovic, M Pavlovic… - Translational …, 2023 - Elsevier
Background The use tumor-derived cell-free DNA extracted from body fluids is being
evaluated for genetic testing in lung cancer. The aim of this study was to explore the …

Pop-Up Paper-Based Biosensor for a Dual-Mode Lung Cancer ctDNA Assay Based on Novel CoB Nanosheets with Dual-Enzyme Activities and a Portable …

S Yang, J Zhu, L Yang, H Fa, Y Wang, D Huo… - ACS …, 2024 - ACS Publications
Timely monitoring of circulating tumor DNA (ctDNA) in serum is meaningful for personalized
diagnosis and treatment for lung cancer. Cheap and efficient point-of-care testing (POCT) …

Diversity of the Circulating Tumor Markers: Perspectives of a Multimodal Liquid Biopsy

ES Kuligina, GA Yanus, EN Imyanitov - Biochemistry (Moscow), 2024 - Springer
Over the past decade, liquid biopsy (LB) has become a routine diagnostic test essential for
the treatment of malignant tumors of various localizations. Its capabilities include early …

[HTML][HTML] Analysis of Neuron–Specific enolase isozymes in human serum using immunoaffinity purification and liquid chromatography–tandem mass spectrometry …

SAAM Genet, JRE Wolfs, CBAK Vu, M Wolter… - … of Chromatography B, 2023 - Elsevier
Neuron–specific enolase (NSE) is a promising small–cell lung cancer (SCLC) biomarker
composed of αγ and γγ isozyme dimers. As the conventional immunoassays are prone to …

Immunoaffinity Intact Top-Down Mass Spectrometry for Quantification of Neuron-Specific Enolase Gamma, a Low-Abundance Protein Biomarker

SAH van den Wildenberg, SAAM Genet… - Analytical …, 2025 - ACS Publications
Quantification of intact proteins in serum by liquid chromatography high-resolution mass
spectrometry (HRMS) may be a useful alternative to bottom-up LC-MS or conventional …

[HTML][HTML] Liquid Biopsy in gastric cancer: a snapshot of the current state of the art

J Gasparello, C Ceccon, V Angerilli… - The Journal of Liquid …, 2025 - Elsevier
Circulating tumor DNA (ctDNA) is nowadays considered a robust source to search for
druggable tumoral genetic alterations, and in some specific settings liquid biopsy (LB) is …

A quadratic isothermal amplification fluorescent biosensor without intermediate purification for ultrasensitive detection of circulating tumor DNA

Z Wu, H Zheng, Y Bian, J Weng, R Zeng, L Sun - Analyst, 2024 - pubs.rsc.org
Circulating tumor DNA (ctDNA) is an auspicious tumor biomarker released into the
bloodstream by tumor cells, offering abundant information concerning cancer genes. It plays …

[HTML][HTML] Strengths and challenges in current lung cancer care: Timeliness and diagnostic procedures in six Dutch hospitals

SAAM Genet, E Visser, M Youssef-El Soud… - Lung Cancer, 2024 - Elsevier
Objectives Timely diagnosis of lung cancer (LC) is crucial to achieve optimal patient care
and outcome. Moreover, the number of procedures required to obtain a definitive diagnosis …

Performance of a Rapid Digital PCR Test for the Detection of Non-Small Cell Lung Cancer (NSCLC) Variants

AF Al Mana, K Culp, A Keeler, O Perrera… - Molecular Diagnosis & …, 2024 - Springer
Background Next-generation sequencing is widely used for comprehensive molecular
profiling for many cancers including lung cancer. However, the complex workflows and long …