CK2 is a constitutively active Ser/Thr protein kinase, which phosphorylates hundreds of
substrates, controls several signaling pathways, and is implicated in a plethora of human …

CK2 genes are overexpressed in many human cancers, and most often overexpression is
associated with worse prognosis. Site-specific expression in mice leads to cancer …

Protein kinase CK2 is a small family of protein kinases that has been implicated in an
expanding array of biological processes. While it is widely accepted that CK2 is a regulatory …

Diffuse and uncontrollable brain invasion is a hallmark of glioblastoma (GBM), but its
mechanism is understood poorly. We developed a 3D ex vivo organotypic model to study …

Protein synthesis can be segmented into distinct phases comprising mRNA translation
initiation, elongation, and termination. Translation initiation is a highly regulated and rate …

Protein kinase CK2 is a highly conserved and constitutively active Ser/Thr-kinase that
phosphorylates a large number of substrates, resulting in increased cell proliferation and …

CK2 is a constitutively active Ser/Thr protein kinase which phosphorylates hundreds of
substrates. Since they are primarily related to survival and proliferation pathways, the best …

Cancer is a leading cause of death worldwide. Casein kinase 2 (CK2) is commonly
dysregulated in cancer, impacting diverse molecular pathways. CK2 is a highly conserved …

Objective. The aim of the present investigation was to study the effect of hypoxia on the
expression of genes encoding endothelin-1 (EDN1) and its cognate receptors (EDNRA and …

We investigated the intracellular metabolic fluxes of protein kinase CK2-activating (Cα OE)
cells and role of lactate dehydrogenase A (LDHA) as a contributor of tumorigenesis after …