This review provides an overview of the biochemistry of thiol redox couples and the
significance of thiol redox homeostasis in neurodegenerative disease. The discussion is …

Neuronal survival depends on multiple factors that comprise a well‐fueled energy
metabolism, trophic input, clearance of toxic substances, appropriate redox environment …

Activated microglia can phagocytose dying, stressed, or excess neurons and synapses via
the phagocytic receptor Mer tyrosine kinase (MerTK). Galectin-3 (Gal-3) can cross-link …

Diabetic retinopathy (DR) is the leading cause of blindness among the working‑age
population in several countries. Despite the available treatments, some patients are …

Cardiotonic steroid (CTS) ouabain is a well‐established inhibitor of Na, K‐ATPase capable
of inducing signalling processes including changes in the activity of the mitogen activated …

In central nervous system cells, low molecular weight fractions (LMWF) from snake venoms
can inhibit changes in mitochondrial membrane permeability, preventing the diffusion of …

It is well known that estrogen exerts neuroprotective effect against various neuronal
damages. However, the estrogen receptor (ER) that mediates estrogen neuroprotection has …

Cobalt protoporphyrin (CoPP) is a potent HO-1 inducer and generally known to be an
antioxidant in various cell types. Little is known about the CoPP-induced cyclooxygenase-2 …

The tyrosine kinase inhibitor Sunitinib is used to treat cancer and is linked to severe adverse
cardiovascular events. Mitogen activated kinase kinase 7 (MKK7) is involved in the …

Objective To investigate the neuroprotective effects of Fructus Chebulae extract using both
in vivo and in vitro models of cerebral ischemia. Methods As an in vitro model, oxygen …