[HTML][HTML] Pearls and pitfalls of pulsed field ablation

S Hartl, N Reinsch, A Füting… - Korean Circulation …, 2023 - synapse.koreamed.org
Pulsed field ablation (PFA) was recently rediscovered as an emerging treatment modality for
the ablation of cardiac arrhythmias. Ultra-short high voltage pulses are leading to …

Overview of cardiac arrhythmias and treatment strategies

J Kingma, C Simard, B Drolet - Pharmaceuticals, 2023 - mdpi.com
Maintenance of normal cardiac rhythm requires coordinated activity of ion channels and
transporters that allow well-ordered propagation of electrical impulses across the …

Establishing irreversible electroporation electric field potential threshold in a suspension in vitro model for cardiac and neuronal cells

S Avazzadeh, B O'Brien, K Coffey… - Journal of Clinical …, 2021 - mdpi.com
Aims: Irreversible electroporation is an ablation technique being adapted for the treatment of
atrial fibrillation. Currently, there are many differences reported in the in vitro and pre-clinical …

Ablation modalities for therapeutic intervention in arrhythmia-related cardiovascular disease: focus on electroporation

S McBride, S Avazzadeh, AM Wheatley… - Journal of Clinical …, 2021 - mdpi.com
Targeted cellular ablation is being increasingly used in the treatment of arrhythmias and
structural heart disease. Catheter-based ablation for atrial fibrillation (AF) is considered a …

In silico modelling to assess the electrical and thermal disturbance provoked by a metal intracoronary stent during epicardial pulsed electric field ablation

A González-Suárez, JJ Pérez, B O'Brien… - Journal of Cardiovascular …, 2022 - mdpi.com
Background: Pulsed Electric Field (PEF) ablation has been recently proposed to ablate
cardiac ganglionic plexi (GP) aimed to treat atrial fibrillation. The effect of metal intracoronary …

Electroporation parameters for human cardiomyocyte ablation in vitro

JM Baena-Montes, T O'Halloran, C Clarke… - Journal of …, 2022 - mdpi.com
Cardiac ablation with irreversible electroporation (IRE) is quickly being established as a
modality of choice for atrial fibrillation treatment. While it has not yet been optimised, IRE has …

Full torso and limited-domain computer models for epicardial pulsed electric field ablation

A González-Suárez, RM Irastorza, S Deane… - Computer Methods and …, 2022 - Elsevier
Abstract Background and objectives Pulsed Electric Field (PEF) ablation has been proposed
as a non-thermal energy to treat atrial fibrillation (AF) by ablation of ganglionated plexi using …

Establishing electroporation thresholds for targeted cell specific cardiac ablation in a 2D culture model

S Avazzadeh, MH Dehkordi, P Owens… - Journal of …, 2022 - Wiley Online Library
Background Irreversible electroporation has emerged as a new modality to overcome issues
associated with other energy sources for cardiac ablation. Strong evidence on the optimal …

Pathophysiology and clinical relevance of atrial myopathy

MRL Tubeeckx, GW De Keulenaer… - Basic Research in …, 2024 - Springer
Atrial myopathy is a condition that consists of electrical, structural, contractile, and autonomic
remodeling of the atria and is the substrate for development of atrial fibrillation, the most …

Pulsed electric field ablation of epicardial autonomic ganglia: Computer analysis of monopolar electric field across the tissues involved

A González-Suárez, B O'Brien, M O'Halloran, A Elahi - Bioengineering, 2022 - mdpi.com
Background and objectives: Pulsed Electric Field (PEF) ablation has been proposed as a
non-thermal energy to treat atrial fibrillation (AF) by epicardial ablation of ganglionated plexi …