Sulfonamide compounds, also known as sulfa drugs, are a significant class of synthetic
bacteriostatic antimicrobials and were the primary source of therapy against bacterial …

The previously unknown difluoromethyl diazirines and the previously neglected
trifluoromethyl-aliphatic diazirines were synthesized and characterized. Model photolabeling …

A series of heterocyclic compounds with a sulfonamide moiety were synthesized from
reaction of enaminone 4 with active methylene compounds, glycine derivatives, 1, 4 …

MTT assay and flow cytometry analysis were used to examine the anti-liver (HepG2) and
anti-breast cancer (MCF-7) activities of twelve compounds derived from 2-thioxo-4 …

New substituted imidazolidinone sulfonamides have been developed using a rational drug
design strategy. Predictive QSAR models for the search of new antibacterials were created …

Here, we describe machine learning models, predicted ADMET properties, and analysis in
vitro activity of selected 4-iminohydantoin sulfamide derivatives with different N-substitution …

A series of novel 2‐oxoimidazolidine derivatives were synthesized and their antiviral
activities against BK human polyomavirus type 1 (BKPyV) were evaluated in vitro. Bioassays …

A number of sulfamides were obtained by reaction interaction of (5-(dichloromethylene)-2-
oxoimidazolidin-4-ylidene) sulfamoyl chloride with anilines, benzylamines, Boc-protected …

With the emergence of multidrug-resistant bacterial strains, there is an urgent need to find
antibacterial agents directed at alternative molecular targets. A series of 4-iminohydantoin …

The previously unknown difluoromethyl-and the previously neglected trifluoromethyl-
aliphatic diazirines were synthesized and characterized. Model photolabeling experiments …