AR Kumar, AR Devan, B Nair, BS Vinod… - Molecular biology …, 2021 - Springer
Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar" of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …
Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly expressed in cancer. The expression of HSPs in tumor cells has been shown to be …
The J-domain proteins (JDP) form the largest protein family among cellular chaperones. In cooperation with the Hsp70 chaperone system, these co-chaperones orchestrate a plethora …
H Liu, Z Zhang, Y Huang, W Wei, S Ning, J Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Aim We aimed to develop and validate a comprehensive nomogram containing pre- treatment plasma HSP90AA1 to predict the risk of breast cancer onset and metastasis …
H Javid, P Hashemian, S Yazdani… - Journal of Cellular …, 2022 - Wiley Online Library
Heat shock proteins (HSPs) are a large molecular chaperone family classified by their molecular weights, including HSP27, HSP40, HSP60, HSP70, HSP90, and HSP110. HSPs …
BJ Lang, ME Guerrero-Giménez, TL Prince… - International journal of …, 2019 - mdpi.com
Heat shock protein (HSP) synthesis is switched on in a remarkably wide range of tumor cells, in both experimental animal systems and in human cancer, in which these proteins …
H Ghozlan, A Cox, D Nierenberg, S King… - Frontiers in Cell and …, 2022 - frontiersin.org
Maintenance of the cellular proteome or proteostasis is an essential process that when deregulated leads to diseases like neurological disorders and cancer. Central to …
The human innate host defense molecules, SP-A1 and SP-A2 variants, differentially affect survival after infection in mice and in lung transplant patients. SP-A interacts with the …
AE Showalter, AC Martini, D Nierenberg, K Hosang… - Scientific reports, 2020 - nature.com
Abstract Chaperonin-containing TCP-1 (CCT or TRiC) is a multi-subunit complex that folds many of the proteins essential for cancer development. CCT is expressed in diverse cancers …