Cell motility in cancer invasion and metastasis: insights from simple model organisms

CH Stuelten, CA Parent, DJ Montell - Nature Reviews Cancer, 2018 - nature.com
Metastasis remains the greatest challenge in the clinical management of cancer. Cell motility
is a fundamental and ancient cellular behaviour that contributes to metastasis and is …

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness

E Sánchez-Tilló, Y Liu, O de Barrios, L Siles… - Cellular and molecular …, 2012 - Springer
Cancer is a complex multistep process involving genetic and epigenetic changes that
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …

CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics

A Luna, F Elloumi, S Varma, Y Wang… - Nucleic acids …, 2021 - academic.oup.com
Abstract CellMiner Cross-Database (CellMinerCDB, discover. nci. nih. gov/cellminercdb)
allows integration and analysis of molecular and pharmacological data within and across …

CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set

WC Reinhold, M Sunshine, H Liu, S Varma, KW Kohn… - Cancer research, 2012 - AACR
High-throughput and high-content databases are increasingly important resources in
molecular medicine, systems biology, and pharmacology. However, the information usually …

[HTML][HTML] Expanding roles of ZEB factors in tumorigenesis and tumor progression

E Sánchez-Tilló, L Siles, O De Barrios… - American journal of …, 2011 - ncbi.nlm.nih.gov
The ZEB family of transcription factors regulates key factors during embryonic development
and cell differentiation but their role in cancer biology has only more recently begun to be …

Upregulation of CD36, a fatty acid translocase, promotes colorectal cancer metastasis by increasing MMP28 and decreasing E-cadherin expression

J Drury, PG Rychahou, CO Kelson, ME Geisen, Y Wu… - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer is the second leading cause of cancer-related death in
the world. Upregulation of fatty acid metabolism is a hallmark of cancer and recent studies …

[HTML][HTML] AURKA induces EMT by regulating histone modification through Wnt/β-catenin and PI3K/Akt signaling pathway in gastric cancer

X Liu, Z Li, Y Song, R Wang, L Han, Q Wang, K Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gastric cancer, a highly invasive and aggressive malignancy, is the third leading cause of
death from cancer worldwide. Genetic association studies have successfully revealed …

miR‐134 targets PDCD7 to reduce E‐cadherin expression and enhance oral cancer progression

SY Peng, HF Tu, CC Yang, CH Wu… - … journal of cancer, 2018 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is a common malignancy worldwide. This study
clarified the oncogenic role of miR‐134 in OSCC. Reporter assays, using both wild‐type and …

Hypoxia promotes the invasion and metastasis of laryngeal cancer cells via EMT

J Zuo, J Wen, M Lei, M Wen, S Li, X Lv, Z Luo, G Wen - Medical oncology, 2016 - Springer
The purpose of this study is to explore the role of hypoxia on the invasion and metastasis of
laryngeal carcinoma. The invasion and migration ability of laryngeal cancer SCC10A cell …

Circular RNA hsa_circ_0001178 facilitates the invasion and metastasis of colorectal cancer through upregulating ZEB1 via sponging multiple miRNAs

C Ren, Z Zhang, S Wang, W Zhu, P Zheng… - Biological …, 2020 - degruyter.com
Metastasis is the main cause of increasing cancer morbidity and mortality. However, the
underlying mechanism of cancer metastasis remains largely unknown. In the present study …