The 'obesity epidemic'represents a major global socioeconomic burden that urgently calls
for a better understanding of the underlying causes of increased weight gain and its …

Neuropeptides released by hypothalamic neurons play a major role in the regulation of
feeding, acting both within the hypothalamus, and at other appetite regulating centres …

This review aims to give a brief overview of NPY receptor distribution and physiology in the
brain and summarizes series of studies, test by test and region by region, aimed at …

Neuropeptide Y (NPY) is one the most potent orexigenic peptides found in the brain. It
stimulates food intake with a preferential effect on carbohydrate intake. It decreases latency …

Kennedy hypothesized nearly 50 y ago that negative feedback regulation of body fat stores
involves hormones that circulate in proportion to adiposity and enter the brain, where they …

The peptidic neurotransmitter neuropeptide Y (NPY) has received great attention because it
has been implicated in the regulation of several organ systems. In particular, NPY is …

Neuropeptide Y (NPY) is a highly conserved neuropeptide with orexigenic actions in
discrete hypothalamic nuclei that plays a role in regulating energy homeostasis. NPY …

Neuropeptide Y (NPY) mediates its physiological effects through at least four receptors
known as Y1, Y2, Y4, and Y5. This peptide is one of the most abundant peptides in the …

The neuropeptide Y (NPY) system is a multireceptor/multiligand system consisting of four
receptors in humans (hY1, hY2, hY4, hY5) and three agonists (NPY, PYY, PP) that activate …

Hypothalamic neuropeptide Y (NPY) and proopiomelanocortin (POMC) neurons act to
sense and coordinate the brain's responses to metabolic cues. One neuronal network that is …