The roles of inflammation in keloid and hypertrophic scars

ZC Wang, WY Zhao, Y Cao, YQ Liu, Q Sun… - Frontiers in …, 2020 - frontiersin.org
The underlying mechanisms of wound healing are complex but inflammation is one of the
determining factors. Besides its traditional role in combating against infection upon injury …

Botulinum toxin type A for the treatment and prevention of hypertrophic scars and keloids: updated review

LM Kasyanju Carrero, W Ma, H Liu… - Journal of cosmetic …, 2019 - Wiley Online Library
Abstract Botulinum Toxin Type A is a potent neurotoxin that is produced by a gram‐positive
bacteria clostridium botulinum. Its utilization in the treatment of various medical condition …

[HTML][HTML] Intralesional injection of botulinum toxin type A compared with intralesional injection of corticosteroid for the treatment of hypertrophic scar and keloid: a …

M Bi, P Sun, D Li, Z Dong, Z Chen - Medical science monitor …, 2019 - ncbi.nlm.nih.gov
Background The optimal treatment for hypertrophic scar and keloid remains controversial.
Therefore, the aim of this systematic review and meta-analysis was to compare the …

The use of botulinum toxin in keloid scar management: a literature review

C Sohrabi, I Goutos - Scars, Burns & Healing, 2020 - journals.sagepub.com
Introduction: Administration of botulinum toxin is an increasingly popular procedure in the
medical and aesthetic field. There is emerging evidence that it can influence fibroblast …

The efficacy and safety of botulinum toxin injections in preventing postoperative scars and improving scar quality: a systematic review and meta-analysis

Z Qiao, H Yang, L Jin, S Li, X Wang - Aesthetic Plastic Surgery, 2021 - Springer
Background Scars exposed on the body surface lead to a large psychological burden on
patients. However, no satisfactory scar treatments exist. Botulinum toxin type A is a …

Evaluation of botulinum toxin type A for treating post burn hypertrophic scars and keloid in children: An intra‐patient randomized controlled study

AA Tawfik, RA Ali - Journal of cosmetic dermatology, 2023 - Wiley Online Library
Background Consequently, the management of post burn hypertrophic scars and keloid in
children are a great challenge for the physicians, parents, and children themselves. Purpose …

Botulinum toxin type A suppresses pro-fibrotic effects via the JNK signaling pathway in hypertrophic scar fibroblasts

GS Park, MK An, JH Yoon, SS Park, SH Koh… - Archives of …, 2019 - Springer
Hypertrophic scar is a dermal fibroproliferative disease characterized by the overproduction
and deposition of extracellular matrix, and the hyperproliferation and enhanced …

Efficacy of botulinum toxin type A in improving scar quality and wound healing: a systematic review and meta-analysis of randomized controlled trials

X Guo, G Song, D Zhang, X Jin - Aesthetic Surgery Journal, 2020 - academic.oup.com
Background Botulinum toxin type A-induced “chemoimmobilization” has long been utilized
for improved scar quality and wound healing; however, current evidence is limited to small …

Early postoperative interventions in the prevention and management of thyroidectomy scars

N Hong, B Sheng, P Yu - Frontiers in Physiology, 2024 - frontiersin.org
Thyroidectomy scars, located on the exposed site, can cause distress in patients. Owing to
the cosmetic importance of thyroidectomy scars, many studies have been conducted on its …

The Safety and efficacy of botulinum toxin type A injection for postoperative scar prevention: A systematic review and meta‐analysis

W Yang, G Li - Journal of cosmetic dermatology, 2020 - Wiley Online Library
Background Active prevention and treatment of scars are particularly important. Several
studies have used botulinum toxin type A (BTXA) to prevent postoperative scarring. The aim …