Laboratory investigations provide physicians with objective data to aid in disease diagnosis,
clinical decision making, and patient follow up. Clinical interpretation of laboratory test …

BACKGROUND Concern has been raised about the quality of available biological variation
(BV) estimates and the effect of their application in clinical practice. A European Federation …

The association between micronutrient intake and the risk of periodontitis has received
much attention in recent years. However, most studies focused on the linear relationship …

The concentration of biomolecules in living systems shows numerous systematic and
random variations. Systematic variations can be classified based on the frequency of …

Background: Numerical data on the components of biological variation (BV) have many uses
in laboratory medicine, including in the setting of analytical quality specifications, generation …

Background and aims The gold standard for measuring LDL-C is impractical for routine use
while direct measurements have numerous shortcomings. This study investigated the …

Iron deficiency anemia (IDA) has detrimental effects on individuals and societies worldwide.
A standard sandwich assay (SA) for the detection of soluble transferrin receptor (sTfR), a …

BACKGROUND Age-specific reference intervals (RIs) have been developed for
biochemistry analytes in children. However, the ability to interpret results from multiple …

Reference intervals provide valuable information to medical practitioners in their
interpretation of quantitative laboratory test results, and are critical in the assessment of …

The aims of this study are: 1) to use the data included in the biological variation (BV)
database to address the usability of BV estimates; and 2) to use different examples from the …