Autoimmune diseases disproportionately affect females more than males. The XX sex
chromosome complement is strongly associated with susceptibility to autoimmunity. Xist …

Busy schedules, changes in lifestyle, and the rise in consumption of ultra-processed foods
have resulted in inadequate bioactive compounds on the consumer's plate. This deficiency …

Immunosuppressive myeloid cells hinder immunotherapeutic efficacy in tumors, but the
precise mechanisms remain undefined. Here, by performing single-cell RNA sequencing in …

Tolerogenic dendritic cells play a critical role in promoting antigen-specific tolerance via
dampening of T cell responses, induction of pathogenic T cell exhaustion and antigen …

The new food-derived bio-functional peptides are urgently needed globally, but the
separation and purification process for obtaining the immunopeptides from food is low …

We have established a platform for the isolation of tumour-specific TCR from T cells of
patients who experienced clinical benefit from cancer vaccination. In this review we will …

Cytotoxic T lymphocytes (CTLs) mediate host defense against viral and intracellular
bacterial infections and tumors. However, the magnitude of CTL response and their function …

Background Our previous research found that YAP1 may have a role in multidrug resistance
(MDR) in small cell lung cancer (SCLC). However, its underlying mechanism is unknown …

Lentiviral vectors (LVs) are highly efficient at inducing CD8+ T cell responses. However, LV-
encoded antigens are processed inside the cytosol of antigen-presenting cells, which does …

The incidence of endometrial cancer is increasing each year, and treatment effects are poor
for patients with advanced and specific subtypes. Exploring immune infiltration-related …