[HTML][HTML] Boolean modelling as a logic-based dynamic approach in systems medicine
Molecular mechanisms of health and disease are often represented as systems biology
diagrams, and the coverage of such representation constantly increases. These static …
diagrams, and the coverage of such representation constantly increases. These static …
Boolean dynamic modeling of cancer signaling networks: Prognosis, progression, and therapeutics
S Sherekar, GA Viswanathan - Computational and systems …, 2021 - Wiley Online Library
Cancer is a multifactorial disease. Aberrant functioning of the underlying complex signaling
network that orchestrates cellular response to external or internal cues governs incidence …
network that orchestrates cellular response to external or internal cues governs incidence …
The CoLoMoTo interactive notebook: accessible and reproducible computational analyses for qualitative biological networks
Analysing models of biological networks typically relies on workflows in which different
software tools with sensitive parameters are chained together, many times with additional …
software tools with sensitive parameters are chained together, many times with additional …
Gene regulatory networks exhibit several kinds of memory: Quantification of memory in biological and random transcriptional networks
Gene regulatory networks (GRNs) process important information in developmental biology
and biomedicine. A key knowledge gap concerns how their responses change over time …
and biomedicine. A key knowledge gap concerns how their responses change over time …
Identification of control targets in Boolean molecular network models via computational algebra
Background Many problems in biomedicine and other areas of the life sciences can be
characterized as control problems, with the goal of finding strategies to change a disease or …
characterized as control problems, with the goal of finding strategies to change a disease or …
A network modeling approach to elucidate drug resistance mechanisms and predict combinatorial drug treatments in breast cancer
Background Mechanistic models of within-cell signal transduction networks can explain how
these networks integrate internal and external inputs to give rise to the appropriate cellular …
these networks integrate internal and external inputs to give rise to the appropriate cellular …
Computing attractors of large-scale asynchronous Boolean networks using minimal trap spaces
VG Trinh, K Hiraishi, B Benhamou - Proceedings of the 13th ACM …, 2022 - dl.acm.org
Boolean Networks (BNs) play a crucial role in modeling, analyzing, and controlling
biological systems. One of the most important problems on BNs is to compute all the …
biological systems. One of the most important problems on BNs is to compute all the …
Taming asynchrony for attractor detection in large Boolean networks
Boolean networks is a well-established formalism for modelling biological systems. A vital
challenge for analyzing a Boolean network is to identify all the attractors. This becomes …
challenge for analyzing a Boolean network is to identify all the attractors. This becomes …
[图书][B] Algorithms for analysis, inference, and control of Boolean networks
T Akutsu - 2018 - World Scientific
The Boolean network (BN) is a mathematical model of genetic networks and is based on
Boolean functions. Boolean functions are functions on the Boolean domain that consists of …
Boolean functions. Boolean functions are functions on the Boolean domain that consists of …
Phenotype Control techniques for Boolean gene regulatory networks
D Plaugher, D Murrugarra - Bulletin of mathematical biology, 2023 - Springer
Modeling cell signal transduction pathways via Boolean networks (BNs) has become an
established method for analyzing intracellular communications over the last few decades …
established method for analyzing intracellular communications over the last few decades …