Brain function relies on the generation of a large variety of morphologically and functionally
diverse, but specific, neuronal synapses. Here we show that, in mice, the initial formation of …

Astrocytes are vital support cells that ensure proper brain function. In brain disease,
astrocytes reprogram into a reactive state that alters many of their cellular roles. A long …

The mature mammalian cortex is composed of 6 architecturally and functionally distinct
layers. Two key steps in the assembly of this layered structure are the initial establishment of …

Adeno-associated viruses (AAVs) are used in a wide array of experimental situations for
driving expression of biosensors, recombinases, and opto-/chemo-genetic actuators in the …

Cell-free gene expression systems are increasingly important in fundamental research and
biomanufacturing, offering a versatile platform for studying gene circuits and bio …

Synthetic genetic circuits have revolutionized numerous fields, ranging from academic
research and point-of-care diagnostics to disease therapeutics and industrial …