Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

Objective To review the literature on psychological and biological findings on resilience (ie
the successful adaptation and swift recovery after experiencing life adversities) at the level of …

Neurons in the mature human central nervous system (CNS) perform a wide range of motor,
sensory, regulatory, behavioral, and cognitive functions. Such diverse functional output …

Aging is a physiological process that can develop without the appearance of concurrent
diseases. However, very frequently, older people suffer from memory loss and an …

During development of the nervous system, the formation of connections (synapses)
between neurons is dependent upon electrical activity in those neurons, and neurotrophic …

Animal research and human neuroimaging studies indicate that stress increases dopamine
levels in brain regions involved in reward processing, and stress also appears to increase …

Protein malnutrition or undernutrition can result in abnormal development of the brain.
Depending on type, age at onset and duration, different structural and functional deficits can …

Depression, also called major depressive disorder, is a neuropsychiatric disorder
jeopardizing an increasing number of the population worldwide. To date, a large number of …

Social isolation gained discussion momentum due to the COVID-19 pandemic. Whereas
many studies address the effects of long-term social isolation in post-weaning and …

Neurotrophins are established molecular mediators of neuronal plasticity in the adult brain.
We analyzed the impact of aging on brain-derived neurotrophic factor (BDNF) and nerve …