[HTML][HTML] Flavonoids in cancer and apoptosis

M Abotaleb, SM Samuel, E Varghese, S Varghese… - Cancers, 2018 - mdpi.com
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

[HTML][HTML] Cytotoxicity of dietary flavonoids on different human cancer types

K Sak - Pharmacognosy reviews, 2014 - ncbi.nlm.nih.gov
Flavonoids are ubiquitous in nature. They are also in food, providing an essential link
between diet and prevention of chronic diseases including cancer. Anticancer effects of …

Site-specific anticancer effects of dietary flavonoid quercetin

K Sak - Nutrition and cancer, 2014 - Taylor & Francis
Food-derived flavonoid quercetin, widely distributed in onions, apples, and tea, is able to
inhibit growth of various cancer cells indicating that this compound can be considered as a …

[HTML][HTML] Nanotechnology innovations to enhance the therapeutic efficacy of quercetin

RGR Pinheiro, M Pinheiro, AR Neves - Nanomaterials, 2021 - mdpi.com
Quercetin is a flavonol present in many vegetables and fruits. Generally, quercetin can be
found in aglycone and glycoside forms, mainly in leaves. The absorption of this compound …

Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo

RI El-Gogary, N Rubio, JTW Wang, WT Al-Jamal… - ACS …, 2014 - ACS Publications
In this work we describe the formulation and characterization of chemically modified
polymeric nanocapsules incorporating the anticancer drug, quercetin, for the passive and …

Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment

CG Vazhappilly, M Amararathna, AC Cyril… - The Journal of …, 2021 - Elsevier
Over the last two decades, several advancements have been made to improve the
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …

Particle-stabilizing effects of flavonoids at the oil− water interface

Z Luo, BS Murray, A Yusoff, MRA Morgan… - Journal of agricultural …, 2011 - ACS Publications
It has been shown that some common food flavonoids can act as excellent stabilizers of oil-
in-water emulsions through their adsorption as water-insoluble particles to the surface of the …

Nanomedicines-tiny particles and big challenges

MRC Marques, Q Choo, M Ashtikar, TC Rocha… - Advanced Drug Delivery …, 2019 - Elsevier
After decades of research, nanotechnology has been used in a broad array of biomedical
products including medical devices, drug products, drug substances, and pharmaceutical …

Novel findings for quercetin encapsulation and preservation with cyclodextrins, liposomes, and drug-in-cyclodextrin-in-liposomes

J Azzi, A Jraij, L Auezova, S Fourmentin… - Food …, 2018 - Elsevier
The low solubility, poor bioavailability, and low chemical stability of quercetin (Quer) are the
main drawbacks that limit its use as a food nutraceutical. In this study, the encapsulation in …

Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation

L Al Shaal, R Shegokar, RH Müller - International journal of pharmaceutics, 2011 - Elsevier
Flavonoids have many positive effects on various cell layers of the skin (eg anti-oxidant, anti-
allergic and anti-inflammatory effects). However, the limiting factor of the use of flavonoids is …