Tryptophan metabolites are known to participate in the regulation of many cells of the
immune system and are involved in various immune-mediated diseases and disorders …

Within the growing field of amino acid metabolism, tryptophan (Trp) catabolism is an area of
increasing interest. Trp is essential for protein synthesis, and its metabolism gives rise to …

On commercial farms, young growing pigs are frequently affected by health problems from
multifactorial origins (eg environmental changes, biosecurity, management, and feed) that …

The inflammasome has been linked to diverse inflammatory and metabolic diseases, and
tight control of inflammasome activation is necessary to avoid excessive inflammation …

Persistent systemic chronic inflammatory conditions are linked with many pathologies,
including cardiovascular diseases (CVDs), a leading cause of death across the globe …

Many, if not all, chronic medical, neurodegenerative and neuroprogressive illnesses are
characterised by chronic immune activation, oxidative and nitrosative stress (O) and …

Delirium, a common form of acute brain dysfunction, is associated with increased morbidity
and mortality, especially in older patients. The underlying pathophysiology of delirium is not …

The degradation of tryptophan (TRP) along the kynurenine pathway plays a crucial role as a
neuro‐and immunomodulatory mechanism in response to inflammatory stimuli, such as …

Ammonia (NH 3) is a major gaseous pollutant in livestock production and has adverse
effects on production, health and welfare of animals. The liver is one of the target organs of …

Poor health is a risk factor for damaging behaviors, but the mechanisms behind this link are
unknown. Injection of pigs with lipopolysaccharide (LPS) can be used to model aspects of …