Executive summary The past six decades have seen remarkable improvements in health
outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young …

Background Public sector austerity measures in many high-income countries mean that
public health budgets are reducing year on year. To help inform the potential impact of these …

Background Assessment of the efficiency of interventions is paramount to achieving
equitable health-care systems. One key barrier to the widespread use of economic …

Cost–effectiveness analysis is used to compare the costs and outcomes of alternative policy
options. Each resulting cost–effectiveness ratio represents the magnitude of additional …

Background: Cost-effectiveness analysis is an important tool for informing treatment
coverage and pricing decisions, yet no consensus exists about what threshold for the …

Background Cost-effectiveness analysis can guide policymakers in resource allocation
decisions. It assesses whether the health gains offered by an intervention are large enough …

Background Although health technology assessment (HTA) systems base their decision
making process either on economic evaluations or comparative clinical benefit assessment …

Objective Our objective was to examine perspective and costing approaches used in cost-
effectiveness analyses (CEAs) and the distribution of reported incremental cost …

The economic evaluation of healthcare interventions requires an assessment of whether the
improvement in health outcomes they offer exceeds the improvement in health that would …

Background Manipulation under anaesthesia and arthroscopic capsular release are costly
and invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We …