Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

The detection of glucose is crucial in the management of diabetes and other medical
conditions but also crucial in a wide range of industries such as food and beverages. The …

Glucose and fructose are closely related simple sugars, but fructose has been associated
more closely with metabolic disease. Until the 1960s, the major dietary source of fructose …

The African naked mole-rat's (Heterocephalus glaber) social and subterranean lifestyle
generates a hypoxic niche. Under experimental conditions, naked mole-rats tolerate hours …

Glucose transporters (GLUTs) at the blood-brain barrier maintain the continuous high
glucose and energy demands of the brain. They also act as therapeutic targets and provide …

The major facilitator superfamily glucose transporters, exemplified by human GLUT1–4,
have been central to the study of solute transport. Using lipidic cubic phase crystallization …

Cellular growth and proliferation depend upon the acquisition and synthesis of specific
metabolites. These metabolites fuel the bioenergy, biosynthesis, and redox potential …

Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …

The protein family of facilitative glucose transporters comprises 14 isoforms that share
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …

Neurons need a continuous supply of glucose, the major source of energy for mammalian
brain metabolism. The central nervous system is protected by three main physiological cell …