Therapeutic siRNA: state of the art
ABSTRACT RNA interference (RNAi) is an ancient biological mechanism used to defend
against external invasion. It theoretically can silence any disease-related genes in a …
against external invasion. It theoretically can silence any disease-related genes in a …
[HTML][HTML] Recent advances in nanotechnology-based COVID-19 vaccines and therapeutic antibodies
COVID-19 has caused a global pandemic and millions of deaths. It is imperative to develop
effective countermeasures against the causative viral agent, SARS-CoV-2 and its many …
effective countermeasures against the causative viral agent, SARS-CoV-2 and its many …
ROS-activatable siRNA-engineered polyplex for NIR-triggered synergistic cancer treatment
Small interfering RNA (siRNA) shows excellent pharmaceutical prospects in treating diverse
life-threatening diseases. Photodynamic therapy (PDT) is a clinically employed noninvasive …
life-threatening diseases. Photodynamic therapy (PDT) is a clinically employed noninvasive …
Design and evaluation of dissolving microneedles for enhanced dermal delivery of propranolol hydrochloride
Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma
(IH), whereas systemic exposure to propranolol has the potential of causing serious adverse …
(IH), whereas systemic exposure to propranolol has the potential of causing serious adverse …
[HTML][HTML] RNAi therapies: Expanding applications for extrahepatic diseases and overcoming delivery challenges
The era of RNA medicine has become a reality with the success of messenger RNA (mRNA)
vaccines against COVID-19 and the approval of several RNA interference (RNAi) agents in …
vaccines against COVID-19 and the approval of several RNA interference (RNAi) agents in …
Smart Physical‐Based Transdermal Drug Delivery System: Towards Intelligence and Controlled Release
Transdermal drug delivery systems based on physical principles have provided a stable,
efficient, and safe strategy for disease therapy. However, the intelligent device with real‐time …
efficient, and safe strategy for disease therapy. However, the intelligent device with real‐time …
Formulation‐based approaches for dermal delivery of vaccines and therapeutic nucleic acids: Recent advances and future perspectives
A growing variety of biological macromolecules are in development for use as active
ingredients in topical therapies and vaccines. Dermal delivery of biomacromolecules offers …
ingredients in topical therapies and vaccines. Dermal delivery of biomacromolecules offers …
Non-invasive strategies for protein drug delivery: Oral, transdermal, and pulmonary
MI Irianti, R Rahmasari, AE Arifianti… - Journal of Applied …, 2020 - japsonline.com
Proteins are the building blocks of human life which involve physiological processes such as
growth, development, metabolism, and reproduction. Despite its role in various biological …
growth, development, metabolism, and reproduction. Despite its role in various biological …
Resveratrol-Loaded Dissolving Microneedles: Fabrication and in vitro Evaluation
B Xing, Q Luo, T Gan, Y Jin, J Feng… - Pharmaceutical …, 2024 - thieme-connect.com
Resveratrol (Res), an active ingredient derived from a multitude of plants, exhibits multiple
pharmacological activities. However, its poor water solubility and low bioavailability present …
pharmacological activities. However, its poor water solubility and low bioavailability present …
Nanoparticles and Their Combination with Physical Methods for Dermal and Transdermal Drug Delivery
N Dragićević, HI Maibach - Percutaneous Absorption, 2021 - taylorfrancis.com
Nanocarriers have been recently intensively studied due to their penetration enhancement
ability regarding dermal and transdermal drug delivery, as well as due to their ability to …
ability regarding dermal and transdermal drug delivery, as well as due to their ability to …