Inflammation, fracture and bone repair

F Loi, LA Córdova, J Pajarinen, T Lin, Z Yao… - Bone, 2016 - Elsevier
The reconstitution of lost bone is a subject that is germane to many orthopedic conditions
including fractures and non-unions, infection, inflammatory arthritis, osteoporosis …

Topography-mediated immunomodulation in osseointegration; Ally or Enemy

S Shirazi, S Ravindran, LF Cooper - Biomaterials, 2022 - Elsevier
Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

Osseointegration of titanium, titanium alloy and zirconia dental implants: current knowledge and open questions

DD Bosshardt, V Chappuis, D Buser - Periodontology 2000, 2017 - Wiley Online Library
Bone healing around dental implants follows the pattern and sequence of
intramembraneous osteogenesis with formation of woven bone first of all followed later by …

Role of implants surface modification in osseointegration: A systematic review

Y Liu, B Rath, M Tingart… - Journal of Biomedical …, 2020 - Wiley Online Library
Long‐term and stable fixation of implants is one of the most important points for a successful
orthopedic surgery in the field of endoprosthesis. Osseointegration (OI), functional …

Inflammation, mesenchymal stem cells and bone regeneration

H Liu, D Li, Y Zhang, M Li - Histochemistry and cell biology, 2018 - Springer
Achieving satisfactory reconstruction of bone remains an important goal in orthopedic and
dental conditions such as bone trauma, osteoporosis, arthritis, osteonecrosis, and …

Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct manners

H Lei, K Schmidt-Bleek, A Dienelt, P Reinke… - Frontiers in …, 2015 - frontiersin.org
Regulatory T cells (Tregs) offer new immunotherapeutic options to control undesired
immune reactions, such as those in transplant rejection and autoimmunity. In addition, tissue …

The role of macrophage in the pathogenesis of osteoporosis

DH Yang, MY Yang - International journal of molecular sciences, 2019 - mdpi.com
Osteoporosis is a systemic disease with progressive bone loss. The bone loss is associated
with an imbalance between bone resorption via osteoclasts and bone formation via …

Multi-functional cerium oxide nanoparticles regulate inflammation and enhance osteogenesis

F Wei, CJ Neal, TS Sakthivel, T Kean, S Seal… - Materials Science and …, 2021 - Elsevier
Oxidative stress increases bone loss and limits repair, in part, through immunoregulation
and the formation and maintenance of low-grade chronic inflammation. The aim of this study …

Osteoimmunology and beyond

L Ginaldi, M De Martinis - Current medicinal chemistry, 2016 - ingentaconnect.com
Objective: Osteoimmunology investigates interactions between skeleton and immune
system. In the light of recent discoveries in this field, a new reading register of osteoporosis …

[HTML][HTML] Implantable blood clot loaded with BMP-2 for regulation of osteoimmunology and enhancement of bone repair

Q Fan, J Bai, H Shan, Z Fei, H Chen, J Xu, Q Ma… - Bioactive Materials, 2021 - Elsevier
The treatment of large-area bone defects still faces many difficulties and challenges. Here,
we developed a blood clot delivery platform loaded with BMP-2 protein (BMP-2@ BC) for …