Design and development of cholinesterase dual inhibitors towards Alzheimer's disease treatment: A focus on recent contributions from computational and theoretical …

FY Adeowo, MM Lawal, HM Kumalo - ChemistrySelect, 2020 - Wiley Online Library
In recent times, review topics on Alzheimer's disease (AD) have received massive attention,
especially on drug design and development of potent inhibitors targeting specific pathway …

Molecular dynamics approach for behavior assessment of chitosan nanoparticles in carrying of donepezil and rivastigmine drug molecules

SV Mousavi, SM Hashemianzadeh - Materials Research Express, 2019 - iopscience.iop.org
Molecular dynamics (MD) simulation was employed to scrutinize behavior of chitosan
nanoparticles (CS-NPs) as a nanocarrier for donepezil and rivastigmine drug molecules …

Synthesis, antioxidant, anticholinesterase activities and molecular docking studies of coumaryl 1, 3-selenazoles derivatives

NZ Alias, MHM Idris, NA Somat, N Mahmud, S Hasan… - 2020 - preprints.org
Inhibition of acetylcholinesterase (AChE) enzyme is a known procedure to treat severe
Alzheimer's disease through increasing the acetylcholine level in the brain and thus slowing …