Exploring role of natural compounds in molecular alterations Associated with Brain Ageing: a perspective towards Nutrition for Ageing Brain

N Siddiqui, A Sharma, A Kesharwani… - Ageing Research …, 2024 - Elsevier
Aging refers to complete deterioration of physiological integrity and function. By midcentury,
adults over 60 years of age and children under 15 years will begin to outnumber people in …

Panax notoginseng: Pharmacological Aspects and Toxicological Issues

C Mancuso - Nutrients, 2024 - mdpi.com
Current evidence suggests a beneficial role of herbal products in free radical-induced
diseases. Panax notoginseng (Burk.) FH Chen has long occupied a leading position in …

Bioactive sphingolipids as emerging targets for signal transduction in cancer development

W Jia, J Yuan, J Zhang, S Li, W Lin, B Cheng - Biochimica et Biophysica …, 2024 - Elsevier
Sphingolipids, crucial components of cellular membranes, play a vital role in maintaining
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …

The role of GZMA as a target of cysteine and biomarker in Alzheimer's disease, pelvic organ prolapse, and tumor progression

Y Li, Z Wang, M Kong, Y Yong, X Yang… - Frontiers in …, 2024 - frontiersin.org
Objective: This study aims to investigate how changes in peripheral blood metabolites in
Alzheimer's Disease (AD) patients affect the development of Pelvic Organ Prolapse (POP) …

TMJ-105, an extract of Carpesium cernuum, induced G2/M phase arrest and apoptosis via the JAK2/STAT3 axis and MAPKs signaling pathway in leukemia HEL cells

X Wei, J Song, Q Rao, Y Huang, Q Liu, J Song, S Feng… - Heliyon, 2024 - cell.com
Leukemia is a malignant tumor of the hematologic system. Studies have shown that
cernuumolide J (TMJ-105), an extract of Carpesium cernuum, has anti-cancer effects, but the …

Berberine: Potential preventive and therapeutic strategies for human colorectal cancer

Y Feng, J Lu, J Jiang, M Wang… - Cell Biochemistry and …, 2024 - Wiley Online Library
Colorectal cancer (CRC) is a common digestive tract tumor, with incidences continuing to
rise. Although modern medicine has extended the survival time of CRC patients, its adverse …